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Comparing Antibody Interfaces to Inform Rational Design of New Antibody Formats

As the current biotherapeutic market is dominated by antibodies, the design of different antibody formats, like bispecific antibodies and other new formats, represent a key component in advancing antibody therapy. When designing new formats, a targeted modulation of pairing preferences is key. Sever...

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Detalles Bibliográficos
Autores principales:	Fernández-Quintero, Monica L., Quoika, Patrick K., Wedl, Florian S., Seidler, Clarissa A., Kroell, Katharina B., Loeffler, Johannes R., Pomarici, Nancy D., Hoerschinger, Valentin J., Bujotzek, Alexander, Georges, Guy, Kettenberger, Hubert, Liedl, Klaus R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826573/ https://www.ncbi.nlm.nih.gov/pubmed/35155578 http://dx.doi.org/10.3389/fmolb.2022.812750

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