Different Pigmentation Risk Loci for High-Risk Monosomy 3 and Low-Risk Disomy 3 Uveal Melanomas

BACKGROUND: Uveal melanoma (UM), a rare malignant tumor of the eye, is predominantly observed in populations of European ancestry. UMs carrying a monosomy 3 (M3) frequently relapse mainly in the liver, whereas UMs with disomy 3 (D3) are associated with more favorable outcome. Here, we explored the U...

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Detalles Bibliográficos
Autores principales: Mobuchon, Lenha, Derrien, Anne-Céline, Houy, Alexandre, Verrier, Thibault, Pierron, Gaëlle, Cassoux, Nathalie, Milder, Maud, Deleuze, Jean-François, Boland, Anne, Scelo, Ghislaine, Cancel-Tassin, Géraldine, Cussenot, Olivier, Rodrigues, Manuel, Noirel, Josselin, Machiela, Mitchell J, Stern, Marc-Henri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826635/
https://www.ncbi.nlm.nih.gov/pubmed/34424336
http://dx.doi.org/10.1093/jnci/djab167

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