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Ranolazine Inhibits Pyroptosis via Regulation of miR-135b in the Treatment of Diabetic Cardiac Fibrosis

Diabetic cardiomyopathy (DCM) is a major cardiovascular complication of diabetes mellitus (DM), and cardiac fibrosis is a characteristic pathological manifestation of DCM. DCM can be exacerbated by pyroptosis, and pyroptosis is a potential target of microRNAs (miRNAs). miR-135b is involved in delayi...

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Detalles Bibliográficos
Autores principales: Ren, Long, Chen, Xi, Nie, Binyang, Qu, Huan, Ju, Jiaming, Bai, Yunlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826643/
https://www.ncbi.nlm.nih.gov/pubmed/35155576
http://dx.doi.org/10.3389/fmolb.2022.806966