Cargando…
Factors associated with faster axial elongation after orthokeratology treatment
BACKGROUND: To study the baseline factors that related to faster axial elongation after orthokeratology (OK) treatment and the characteristics of cases with axial length decrease in a group of myopia children. METHODS: This is a retrospective study. The records of 73 children who had wear OK lens fo...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826659/ https://www.ncbi.nlm.nih.gov/pubmed/35135507 http://dx.doi.org/10.1186/s12886-022-02294-1 |
_version_ | 1784647472170139648 |
---|---|
author | Qi, Ya Liu, Lizhou Li, Yu Zhang, Fengju |
author_facet | Qi, Ya Liu, Lizhou Li, Yu Zhang, Fengju |
author_sort | Qi, Ya |
collection | PubMed |
description | BACKGROUND: To study the baseline factors that related to faster axial elongation after orthokeratology (OK) treatment and the characteristics of cases with axial length decrease in a group of myopia children. METHODS: This is a retrospective study. The records of 73 children who had wear OK lens for at least one year were reviewed. Only the data of right eyes were included. Baseline data included: age, gender, parental myopia, refractive error, corneal power, central corneal thickness, axial length and anterior chamber depth. Corneal power, central corneal thickness, anterior chamber depth and axial length after one-year of OK lens wear were also collected. The related factors affecting axial length change were analyzed. A comparison was made on the cases of axial length increase and axial length decrease. RESULTS: Of the 73 eyes, axial length increased by 0.18 ± 0.17 mm (P < 0.001) after one year of OK lens wear. Correlation analysis showed that one-year axial length change was negatively correlated with age and positively correlated with the parental myopia and baseline myopia. Stepwise multiple linear regression analysis showed that the factors associated with faster axial elongation were lower baseline myopic spherical equivalent (P = 0.018), higher parental myopia degree (P = 0.026), and younger age at the onset of lens wear. (P = 0.039). Nine eyes showed negative axial growth (−0.06 ± 0.04 mm), and had older initial age of lens wear, higher baseline myopic spherical equivalent, and lager baseline corneal power, when compared with cases of axial length increase. CONCLUSIONS: Myopia children with lower baseline myopic spherical equivalent, younger initial age and higher parental myopia had faster axial elongation after orthokeratology treatment. More aggressive treatment should be considered. In children with slow axial elongation, OK lens wear may lead to negative axial growth. Whether there are reasons other than central corneal thinning and choroidal thickening needs further study. |
format | Online Article Text |
id | pubmed-8826659 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-88266592022-02-10 Factors associated with faster axial elongation after orthokeratology treatment Qi, Ya Liu, Lizhou Li, Yu Zhang, Fengju BMC Ophthalmol Research BACKGROUND: To study the baseline factors that related to faster axial elongation after orthokeratology (OK) treatment and the characteristics of cases with axial length decrease in a group of myopia children. METHODS: This is a retrospective study. The records of 73 children who had wear OK lens for at least one year were reviewed. Only the data of right eyes were included. Baseline data included: age, gender, parental myopia, refractive error, corneal power, central corneal thickness, axial length and anterior chamber depth. Corneal power, central corneal thickness, anterior chamber depth and axial length after one-year of OK lens wear were also collected. The related factors affecting axial length change were analyzed. A comparison was made on the cases of axial length increase and axial length decrease. RESULTS: Of the 73 eyes, axial length increased by 0.18 ± 0.17 mm (P < 0.001) after one year of OK lens wear. Correlation analysis showed that one-year axial length change was negatively correlated with age and positively correlated with the parental myopia and baseline myopia. Stepwise multiple linear regression analysis showed that the factors associated with faster axial elongation were lower baseline myopic spherical equivalent (P = 0.018), higher parental myopia degree (P = 0.026), and younger age at the onset of lens wear. (P = 0.039). Nine eyes showed negative axial growth (−0.06 ± 0.04 mm), and had older initial age of lens wear, higher baseline myopic spherical equivalent, and lager baseline corneal power, when compared with cases of axial length increase. CONCLUSIONS: Myopia children with lower baseline myopic spherical equivalent, younger initial age and higher parental myopia had faster axial elongation after orthokeratology treatment. More aggressive treatment should be considered. In children with slow axial elongation, OK lens wear may lead to negative axial growth. Whether there are reasons other than central corneal thinning and choroidal thickening needs further study. BioMed Central 2022-02-08 /pmc/articles/PMC8826659/ /pubmed/35135507 http://dx.doi.org/10.1186/s12886-022-02294-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Qi, Ya Liu, Lizhou Li, Yu Zhang, Fengju Factors associated with faster axial elongation after orthokeratology treatment |
title | Factors associated with faster axial elongation after orthokeratology treatment |
title_full | Factors associated with faster axial elongation after orthokeratology treatment |
title_fullStr | Factors associated with faster axial elongation after orthokeratology treatment |
title_full_unstemmed | Factors associated with faster axial elongation after orthokeratology treatment |
title_short | Factors associated with faster axial elongation after orthokeratology treatment |
title_sort | factors associated with faster axial elongation after orthokeratology treatment |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826659/ https://www.ncbi.nlm.nih.gov/pubmed/35135507 http://dx.doi.org/10.1186/s12886-022-02294-1 |
work_keys_str_mv | AT qiya factorsassociatedwithfasteraxialelongationafterorthokeratologytreatment AT liulizhou factorsassociatedwithfasteraxialelongationafterorthokeratologytreatment AT liyu factorsassociatedwithfasteraxialelongationafterorthokeratologytreatment AT zhangfengju factorsassociatedwithfasteraxialelongationafterorthokeratologytreatment |