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The Role of the Microbiota in Regeneration-Associated Processes

The microbiota, the set of microorganisms associated with a particular environment or host, has acquired a prominent role in the study of many physiological and developmental processes. Among these, is the relationship between the microbiota and regenerative processes in various organisms. Here we i...

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Autores principales: Díaz-Díaz, Lymarie M., Rodríguez-Villafañe, Andrea, García-Arrarás, José E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826689/
https://www.ncbi.nlm.nih.gov/pubmed/35155442
http://dx.doi.org/10.3389/fcell.2021.768783
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author Díaz-Díaz, Lymarie M.
Rodríguez-Villafañe, Andrea
García-Arrarás, José E.
author_facet Díaz-Díaz, Lymarie M.
Rodríguez-Villafañe, Andrea
García-Arrarás, José E.
author_sort Díaz-Díaz, Lymarie M.
collection PubMed
description The microbiota, the set of microorganisms associated with a particular environment or host, has acquired a prominent role in the study of many physiological and developmental processes. Among these, is the relationship between the microbiota and regenerative processes in various organisms. Here we introduce the concept of the microbiota and its involvement in regeneration-related cellular events. We then review the role of the microbiota in regenerative models that extend from the repair of tissue layers to the regeneration of complete organs or animals. We highlight the role of the microbiota in the digestive tract, since it accounts for a significant percentage of an animal microbiota, and at the same time provides an outstanding system to study microbiota effects on regeneration. Lastly, while this review serves to highlight echinoderms, primarily holothuroids, as models for regeneration studies, it also provides multiple examples of microbiota-related interactions in other processes in different organisms.
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spelling pubmed-88266892022-02-10 The Role of the Microbiota in Regeneration-Associated Processes Díaz-Díaz, Lymarie M. Rodríguez-Villafañe, Andrea García-Arrarás, José E. Front Cell Dev Biol Cell and Developmental Biology The microbiota, the set of microorganisms associated with a particular environment or host, has acquired a prominent role in the study of many physiological and developmental processes. Among these, is the relationship between the microbiota and regenerative processes in various organisms. Here we introduce the concept of the microbiota and its involvement in regeneration-related cellular events. We then review the role of the microbiota in regenerative models that extend from the repair of tissue layers to the regeneration of complete organs or animals. We highlight the role of the microbiota in the digestive tract, since it accounts for a significant percentage of an animal microbiota, and at the same time provides an outstanding system to study microbiota effects on regeneration. Lastly, while this review serves to highlight echinoderms, primarily holothuroids, as models for regeneration studies, it also provides multiple examples of microbiota-related interactions in other processes in different organisms. Frontiers Media S.A. 2022-01-26 /pmc/articles/PMC8826689/ /pubmed/35155442 http://dx.doi.org/10.3389/fcell.2021.768783 Text en Copyright © 2022 Díaz-Díaz, Rodríguez-Villafañe and García-Arrarás. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cell and Developmental Biology
Díaz-Díaz, Lymarie M.
Rodríguez-Villafañe, Andrea
García-Arrarás, José E.
The Role of the Microbiota in Regeneration-Associated Processes
title The Role of the Microbiota in Regeneration-Associated Processes
title_full The Role of the Microbiota in Regeneration-Associated Processes
title_fullStr The Role of the Microbiota in Regeneration-Associated Processes
title_full_unstemmed The Role of the Microbiota in Regeneration-Associated Processes
title_short The Role of the Microbiota in Regeneration-Associated Processes
title_sort role of the microbiota in regeneration-associated processes
topic Cell and Developmental Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826689/
https://www.ncbi.nlm.nih.gov/pubmed/35155442
http://dx.doi.org/10.3389/fcell.2021.768783
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