CRM1 Promotes Capsid Disassembly and Nuclear Envelope Translocation of Adenovirus Independently of Its Export Function

After receptor-mediated endocytosis and endosomal escape, adenoviral capsids can travel via microtubule organizing centers to the nuclear envelope. Upon capsid disassembly, viral genome import into nuclei of interphase cells then occurs through nuclear pore complexes, involving the nucleoporins Nup2...

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Detalles Bibliográficos
Autores principales: Lagadec, Floriane, Carlon-Andres, Irene, Ragues, Jessica, Port, Sarah, Wodrich, Harald, Kehlenbach, Ralph H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Virus-Cell Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826800/
https://www.ncbi.nlm.nih.gov/pubmed/34757845
http://dx.doi.org/10.1128/jvi.01273-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826800/
https://www.ncbi.nlm.nih.gov/pubmed/34757845
http://dx.doi.org/10.1128/jvi.01273-21

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