Molecular characterization of methicillin-resistant Staphylococcus aureus genotype ST764-SCCmec type II in Thailand

Methicillin-resistant Staphylococcus aureus (MRSA) is a significant causative agent of hospital-acquired infections. We characterized MRSA isolated from August 2012 to July 2015 from Thammasat University Hospital. Genotypic characterization of MRSA SCCmec type II and III isolates were scrutinized by...

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Autores principales: Kondo, Sumalee, Phokhaphan, Pimonwan, Tongsima, Sissades, Ngamphiw, Chumpol, Phornsiricharoenphant, Worawich, Ruangchai, Wuthiwat, Disratthakit, Areeya, Tingpej, Pholawat, Mahasirimongkol, Surakameth, Lulitanond, Aroonlug, Apisarnthanarak, Anucha, Palittapongarnpim, Prasit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826912/
https://www.ncbi.nlm.nih.gov/pubmed/35136112
http://dx.doi.org/10.1038/s41598-022-05898-1
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author Kondo, Sumalee
Phokhaphan, Pimonwan
Tongsima, Sissades
Ngamphiw, Chumpol
Phornsiricharoenphant, Worawich
Ruangchai, Wuthiwat
Disratthakit, Areeya
Tingpej, Pholawat
Mahasirimongkol, Surakameth
Lulitanond, Aroonlug
Apisarnthanarak, Anucha
Palittapongarnpim, Prasit
author_facet Kondo, Sumalee
Phokhaphan, Pimonwan
Tongsima, Sissades
Ngamphiw, Chumpol
Phornsiricharoenphant, Worawich
Ruangchai, Wuthiwat
Disratthakit, Areeya
Tingpej, Pholawat
Mahasirimongkol, Surakameth
Lulitanond, Aroonlug
Apisarnthanarak, Anucha
Palittapongarnpim, Prasit
author_sort Kondo, Sumalee
collection PubMed
description Methicillin-resistant Staphylococcus aureus (MRSA) is a significant causative agent of hospital-acquired infections. We characterized MRSA isolated from August 2012 to July 2015 from Thammasat University Hospital. Genotypic characterization of MRSA SCCmec type II and III isolates were scrutinized by whole genome sequencing (WGS). The WGS data revealed that the MRSA SCCmec type II isolates belonged to ST764 previously reported mainly in Japan. All of tested isolates contained ACME Type II′, SaPIn2, SaPIn3, seb, interrupted SA1320, and had a virulence gene profile similar to Japan MRSA ST764. Rigorous surveillance of MRSA strains is imperative in Thailand to arrest its potential spread.
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spelling pubmed-88269122022-02-10 Molecular characterization of methicillin-resistant Staphylococcus aureus genotype ST764-SCCmec type II in Thailand Kondo, Sumalee Phokhaphan, Pimonwan Tongsima, Sissades Ngamphiw, Chumpol Phornsiricharoenphant, Worawich Ruangchai, Wuthiwat Disratthakit, Areeya Tingpej, Pholawat Mahasirimongkol, Surakameth Lulitanond, Aroonlug Apisarnthanarak, Anucha Palittapongarnpim, Prasit Sci Rep Article Methicillin-resistant Staphylococcus aureus (MRSA) is a significant causative agent of hospital-acquired infections. We characterized MRSA isolated from August 2012 to July 2015 from Thammasat University Hospital. Genotypic characterization of MRSA SCCmec type II and III isolates were scrutinized by whole genome sequencing (WGS). The WGS data revealed that the MRSA SCCmec type II isolates belonged to ST764 previously reported mainly in Japan. All of tested isolates contained ACME Type II′, SaPIn2, SaPIn3, seb, interrupted SA1320, and had a virulence gene profile similar to Japan MRSA ST764. Rigorous surveillance of MRSA strains is imperative in Thailand to arrest its potential spread. Nature Publishing Group UK 2022-02-08 /pmc/articles/PMC8826912/ /pubmed/35136112 http://dx.doi.org/10.1038/s41598-022-05898-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Kondo, Sumalee
Phokhaphan, Pimonwan
Tongsima, Sissades
Ngamphiw, Chumpol
Phornsiricharoenphant, Worawich
Ruangchai, Wuthiwat
Disratthakit, Areeya
Tingpej, Pholawat
Mahasirimongkol, Surakameth
Lulitanond, Aroonlug
Apisarnthanarak, Anucha
Palittapongarnpim, Prasit
Molecular characterization of methicillin-resistant Staphylococcus aureus genotype ST764-SCCmec type II in Thailand
title Molecular characterization of methicillin-resistant Staphylococcus aureus genotype ST764-SCCmec type II in Thailand
title_full Molecular characterization of methicillin-resistant Staphylococcus aureus genotype ST764-SCCmec type II in Thailand
title_fullStr Molecular characterization of methicillin-resistant Staphylococcus aureus genotype ST764-SCCmec type II in Thailand
title_full_unstemmed Molecular characterization of methicillin-resistant Staphylococcus aureus genotype ST764-SCCmec type II in Thailand
title_short Molecular characterization of methicillin-resistant Staphylococcus aureus genotype ST764-SCCmec type II in Thailand
title_sort molecular characterization of methicillin-resistant staphylococcus aureus genotype st764-sccmec type ii in thailand
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826912/
https://www.ncbi.nlm.nih.gov/pubmed/35136112
http://dx.doi.org/10.1038/s41598-022-05898-1
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