Are COVID-19 Vaccine Boosters Needed? The Science behind Boosters

Waning vaccine-induced immunity coupled with the emergence of SARS-CoV-2 variants has led to increases in breakthrough infections, prompting consideration for vaccine booster doses. Boosters have been reported to be safe and increase SARS-CoV-2-specific neutralizing antibody levels, but how these do...

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Detalles Bibliográficos
Autores principales: Burckhardt, Rachel M., Dennehy, John J., Poon, Leo L. M., Saif, Linda J., Enquist, Lynn W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827020/
https://www.ncbi.nlm.nih.gov/pubmed/34817198
http://dx.doi.org/10.1128/jvi.01973-21
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author Burckhardt, Rachel M.
Dennehy, John J.
Poon, Leo L. M.
Saif, Linda J.
Enquist, Lynn W.
author_facet Burckhardt, Rachel M.
Dennehy, John J.
Poon, Leo L. M.
Saif, Linda J.
Enquist, Lynn W.
author_sort Burckhardt, Rachel M.
collection PubMed
description Waning vaccine-induced immunity coupled with the emergence of SARS-CoV-2 variants has led to increases in breakthrough infections, prompting consideration for vaccine booster doses. Boosters have been reported to be safe and increase SARS-CoV-2-specific neutralizing antibody levels, but how these doses impact the trajectory of the global pandemic and herd immunity is unknown. Information on immunology, epidemiology, and equitable vaccine distribution should be considered when deciding the timing and eligibility for COVID-19 vaccine boosters.
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spelling pubmed-88270202022-02-17 Are COVID-19 Vaccine Boosters Needed? The Science behind Boosters Burckhardt, Rachel M. Dennehy, John J. Poon, Leo L. M. Saif, Linda J. Enquist, Lynn W. J Virol Commentary Waning vaccine-induced immunity coupled with the emergence of SARS-CoV-2 variants has led to increases in breakthrough infections, prompting consideration for vaccine booster doses. Boosters have been reported to be safe and increase SARS-CoV-2-specific neutralizing antibody levels, but how these doses impact the trajectory of the global pandemic and herd immunity is unknown. Information on immunology, epidemiology, and equitable vaccine distribution should be considered when deciding the timing and eligibility for COVID-19 vaccine boosters. American Society for Microbiology 2022-02-09 /pmc/articles/PMC8827020/ /pubmed/34817198 http://dx.doi.org/10.1128/jvi.01973-21 Text en Copyright © 2022 Burckhardt et al. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Commentary
Burckhardt, Rachel M.
Dennehy, John J.
Poon, Leo L. M.
Saif, Linda J.
Enquist, Lynn W.
Are COVID-19 Vaccine Boosters Needed? The Science behind Boosters
title Are COVID-19 Vaccine Boosters Needed? The Science behind Boosters
title_full Are COVID-19 Vaccine Boosters Needed? The Science behind Boosters
title_fullStr Are COVID-19 Vaccine Boosters Needed? The Science behind Boosters
title_full_unstemmed Are COVID-19 Vaccine Boosters Needed? The Science behind Boosters
title_short Are COVID-19 Vaccine Boosters Needed? The Science behind Boosters
title_sort are covid-19 vaccine boosters needed? the science behind boosters
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827020/
https://www.ncbi.nlm.nih.gov/pubmed/34817198
http://dx.doi.org/10.1128/jvi.01973-21
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