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Revisiting the adhesion mechanism of mussel-inspired chemistry

Mussel-inspired chemistry has become an ideal platform to engineer a myriad of functional materials, but fully understanding the underlying adhesion mechanism is still missing. Particularly, one of the most pivotal questions is whether catechol still plays a dominant role in molecular-scale adhesion...

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Autores principales: Zhang, Chao, Xiang, Li, Zhang, Jiawen, Liu, Chang, Wang, Zuankai, Zeng, Hongbo, Xu, Zhi-Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827048/
https://www.ncbi.nlm.nih.gov/pubmed/35282627
http://dx.doi.org/10.1039/d1sc05512g
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author Zhang, Chao
Xiang, Li
Zhang, Jiawen
Liu, Chang
Wang, Zuankai
Zeng, Hongbo
Xu, Zhi-Kang
author_facet Zhang, Chao
Xiang, Li
Zhang, Jiawen
Liu, Chang
Wang, Zuankai
Zeng, Hongbo
Xu, Zhi-Kang
author_sort Zhang, Chao
collection PubMed
description Mussel-inspired chemistry has become an ideal platform to engineer a myriad of functional materials, but fully understanding the underlying adhesion mechanism is still missing. Particularly, one of the most pivotal questions is whether catechol still plays a dominant role in molecular-scale adhesion like that in mussel adhesive proteins. Herein, for the first time, we reveal an unexplored adhesion mechanism of mussel-inspired chemistry that is strongly dictated by 5,6-dihydroxyindole (DHI) moieties, amending the conventional viewpoint of catechol-dominated adhesion. We demonstrate that polydopamine (PDA) delivers an unprecedented adhesion of 71.62 mN m(−1), which surpasses that of many mussel-inspired derivatives and is even 121-fold higher than that of polycatechol. Such a robust adhesion mainly stems from a high yield of DHI moieties through a delicate synergy of leading oxidation and subsidiary cyclization within self-polymerization, allowing for governing mussel-inspired adhesion by the substituent chemistry and self-polymerization manner. The adhesion mechanisms revealed in this work offer a useful paradigm for the exploitation of functional mussel-inspired materials.
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spelling pubmed-88270482022-03-11 Revisiting the adhesion mechanism of mussel-inspired chemistry Zhang, Chao Xiang, Li Zhang, Jiawen Liu, Chang Wang, Zuankai Zeng, Hongbo Xu, Zhi-Kang Chem Sci Chemistry Mussel-inspired chemistry has become an ideal platform to engineer a myriad of functional materials, but fully understanding the underlying adhesion mechanism is still missing. Particularly, one of the most pivotal questions is whether catechol still plays a dominant role in molecular-scale adhesion like that in mussel adhesive proteins. Herein, for the first time, we reveal an unexplored adhesion mechanism of mussel-inspired chemistry that is strongly dictated by 5,6-dihydroxyindole (DHI) moieties, amending the conventional viewpoint of catechol-dominated adhesion. We demonstrate that polydopamine (PDA) delivers an unprecedented adhesion of 71.62 mN m(−1), which surpasses that of many mussel-inspired derivatives and is even 121-fold higher than that of polycatechol. Such a robust adhesion mainly stems from a high yield of DHI moieties through a delicate synergy of leading oxidation and subsidiary cyclization within self-polymerization, allowing for governing mussel-inspired adhesion by the substituent chemistry and self-polymerization manner. The adhesion mechanisms revealed in this work offer a useful paradigm for the exploitation of functional mussel-inspired materials. The Royal Society of Chemistry 2022-01-14 /pmc/articles/PMC8827048/ /pubmed/35282627 http://dx.doi.org/10.1039/d1sc05512g Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Zhang, Chao
Xiang, Li
Zhang, Jiawen
Liu, Chang
Wang, Zuankai
Zeng, Hongbo
Xu, Zhi-Kang
Revisiting the adhesion mechanism of mussel-inspired chemistry
title Revisiting the adhesion mechanism of mussel-inspired chemistry
title_full Revisiting the adhesion mechanism of mussel-inspired chemistry
title_fullStr Revisiting the adhesion mechanism of mussel-inspired chemistry
title_full_unstemmed Revisiting the adhesion mechanism of mussel-inspired chemistry
title_short Revisiting the adhesion mechanism of mussel-inspired chemistry
title_sort revisiting the adhesion mechanism of mussel-inspired chemistry
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827048/
https://www.ncbi.nlm.nih.gov/pubmed/35282627
http://dx.doi.org/10.1039/d1sc05512g
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