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Revisiting the adhesion mechanism of mussel-inspired chemistry
Mussel-inspired chemistry has become an ideal platform to engineer a myriad of functional materials, but fully understanding the underlying adhesion mechanism is still missing. Particularly, one of the most pivotal questions is whether catechol still plays a dominant role in molecular-scale adhesion...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827048/ https://www.ncbi.nlm.nih.gov/pubmed/35282627 http://dx.doi.org/10.1039/d1sc05512g |
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author | Zhang, Chao Xiang, Li Zhang, Jiawen Liu, Chang Wang, Zuankai Zeng, Hongbo Xu, Zhi-Kang |
author_facet | Zhang, Chao Xiang, Li Zhang, Jiawen Liu, Chang Wang, Zuankai Zeng, Hongbo Xu, Zhi-Kang |
author_sort | Zhang, Chao |
collection | PubMed |
description | Mussel-inspired chemistry has become an ideal platform to engineer a myriad of functional materials, but fully understanding the underlying adhesion mechanism is still missing. Particularly, one of the most pivotal questions is whether catechol still plays a dominant role in molecular-scale adhesion like that in mussel adhesive proteins. Herein, for the first time, we reveal an unexplored adhesion mechanism of mussel-inspired chemistry that is strongly dictated by 5,6-dihydroxyindole (DHI) moieties, amending the conventional viewpoint of catechol-dominated adhesion. We demonstrate that polydopamine (PDA) delivers an unprecedented adhesion of 71.62 mN m(−1), which surpasses that of many mussel-inspired derivatives and is even 121-fold higher than that of polycatechol. Such a robust adhesion mainly stems from a high yield of DHI moieties through a delicate synergy of leading oxidation and subsidiary cyclization within self-polymerization, allowing for governing mussel-inspired adhesion by the substituent chemistry and self-polymerization manner. The adhesion mechanisms revealed in this work offer a useful paradigm for the exploitation of functional mussel-inspired materials. |
format | Online Article Text |
id | pubmed-8827048 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | The Royal Society of Chemistry |
record_format | MEDLINE/PubMed |
spelling | pubmed-88270482022-03-11 Revisiting the adhesion mechanism of mussel-inspired chemistry Zhang, Chao Xiang, Li Zhang, Jiawen Liu, Chang Wang, Zuankai Zeng, Hongbo Xu, Zhi-Kang Chem Sci Chemistry Mussel-inspired chemistry has become an ideal platform to engineer a myriad of functional materials, but fully understanding the underlying adhesion mechanism is still missing. Particularly, one of the most pivotal questions is whether catechol still plays a dominant role in molecular-scale adhesion like that in mussel adhesive proteins. Herein, for the first time, we reveal an unexplored adhesion mechanism of mussel-inspired chemistry that is strongly dictated by 5,6-dihydroxyindole (DHI) moieties, amending the conventional viewpoint of catechol-dominated adhesion. We demonstrate that polydopamine (PDA) delivers an unprecedented adhesion of 71.62 mN m(−1), which surpasses that of many mussel-inspired derivatives and is even 121-fold higher than that of polycatechol. Such a robust adhesion mainly stems from a high yield of DHI moieties through a delicate synergy of leading oxidation and subsidiary cyclization within self-polymerization, allowing for governing mussel-inspired adhesion by the substituent chemistry and self-polymerization manner. The adhesion mechanisms revealed in this work offer a useful paradigm for the exploitation of functional mussel-inspired materials. The Royal Society of Chemistry 2022-01-14 /pmc/articles/PMC8827048/ /pubmed/35282627 http://dx.doi.org/10.1039/d1sc05512g Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/ |
spellingShingle | Chemistry Zhang, Chao Xiang, Li Zhang, Jiawen Liu, Chang Wang, Zuankai Zeng, Hongbo Xu, Zhi-Kang Revisiting the adhesion mechanism of mussel-inspired chemistry |
title | Revisiting the adhesion mechanism of mussel-inspired chemistry |
title_full | Revisiting the adhesion mechanism of mussel-inspired chemistry |
title_fullStr | Revisiting the adhesion mechanism of mussel-inspired chemistry |
title_full_unstemmed | Revisiting the adhesion mechanism of mussel-inspired chemistry |
title_short | Revisiting the adhesion mechanism of mussel-inspired chemistry |
title_sort | revisiting the adhesion mechanism of mussel-inspired chemistry |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827048/ https://www.ncbi.nlm.nih.gov/pubmed/35282627 http://dx.doi.org/10.1039/d1sc05512g |
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