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Combating amyloid-induced cellular toxicity and stiffness by designer peptidomimetics

Amyloid beta (Aβ) aggregation species-associated cellular stress instigates cytotoxicity and adverse cellular stiffness in neuronal cells. The study and modulation of these adverse effects demand immediate attention to tackle Alzheimer's disease (AD). We present a de novo design, synthesis and...

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Detalles Bibliográficos
Autores principales: Konar, Mouli, Ghosh, Debasis, Samanta, Sourav, Govindaraju, Thimmaiah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827053/
https://www.ncbi.nlm.nih.gov/pubmed/35360886
http://dx.doi.org/10.1039/d1cb00235j