Myocardin/microRNA-30a/Beclin1 signaling controls the phenotypic modulation of vascular smooth muscle cells by regulating autophagy

Upon vascular injury, vascular smooth muscle cells (VSMCs) change from a contractile phenotype to a synthetic phenotype, thereby leading to atherogenesis and arterial restenosis. Myocardin (MYOCD) is essential for maintaining the contractile phenotype of VSMCs. Deletion of MYOCD in VSMCs triggers au...

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Detalles Bibliográficos
Autores principales: Shi, Danyang, Ding, Jinhua, Xie, Shouqiang, Huang, Lei, Zhang, Hongmin, Chen, Xiaojie, Ren, Xuejun, Zhou, Sa, He, Hongpeng, Ma, Wenjian, Zhang, Tongcun, Wang, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827084/
https://www.ncbi.nlm.nih.gov/pubmed/35136037
http://dx.doi.org/10.1038/s41419-022-04588-0

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