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Transcriptional landscape of circulating platelets from patients with COVID-19 reveals key subnetworks and regulators underlying SARS-CoV-2 infection: implications for immunothrombosis

BACKGROUND: Thrombosis and coagulopathy are pervasive pathological features of coronavirus disease 2019 (COVID-19), and thrombotic complications are a sign of severe COVID-19 disease and are associated with multiple organ failure and increased mortality. Platelets are essential cells that regulate h...

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Detalles Bibliográficos
Autores principales: Ji, Weiping, Chen, Lu, Yang, Wei, Li, Ke, Zhao, Jingting, Yan, Congcong, You, Cancan, Jiang, Minghua, Zhou, Meng, Shen, Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827164/
https://www.ncbi.nlm.nih.gov/pubmed/35139909
http://dx.doi.org/10.1186/s13578-022-00750-5