Cargando…

Socioeconomic differences in metabolic syndrome development: examining the mediating role of chronic stress using the Lifelines Cohort Study

BACKGROUND: Metabolic syndrome (MetS) development strongly varies based on individuals’ socioeconomic position (SEP), but to date, no studies have assessed the mediating role of perceived stress from long-term difficulties (chronic stress) in this association. The aim of this study is to examine the...

Descripción completa

Detalles Bibliográficos
Autores principales: Hoveling, Liza A., Liefbroer, Aart C., Bültmann, Ute, Smidt, Nynke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827257/
https://www.ncbi.nlm.nih.gov/pubmed/35135520
http://dx.doi.org/10.1186/s12889-022-12684-1
_version_ 1784647591014694912
author Hoveling, Liza A.
Liefbroer, Aart C.
Bültmann, Ute
Smidt, Nynke
author_facet Hoveling, Liza A.
Liefbroer, Aart C.
Bültmann, Ute
Smidt, Nynke
author_sort Hoveling, Liza A.
collection PubMed
description BACKGROUND: Metabolic syndrome (MetS) development strongly varies based on individuals’ socioeconomic position (SEP), but to date, no studies have assessed the mediating role of perceived stress from long-term difficulties (chronic stress) in this association. The aim of this study is to examine the mediating role of chronic stress in the associations of the SEP measures education, occupational prestige and income, with MetS development, and whether associations between chronic stress and MetS are moderated by sex. METHODS: We used an adult subsample (n = 53,216) from the Lifelines Cohort Study without MetS at baseline. MetS development was measured 3.9 years after baseline (follow-up), and defined according to National Cholesterol Education Program’s Adult Treatment Panel III (NCEP-ATPIII) criteria. Direct associations between SEP, chronic stress and MetS development were estimated using multivariable logistic and linear regression analyses, and were adjusted for age, sex, the other SEP measures, and time between baseline and follow-up. The mediating percentages of chronic stress explaining the associations between SEP and MetS development were estimated using the Karlson-Holm-Breen method. RESULTS: Upon follow-up, 7.4% of the participants had developed MetS. Years of education and occupational prestige were inversely associated with MetS development. Chronic stress suppressed the association between education and MetS development (5.6%), as well as the association between occupational prestige and MetS development (6.2%). No effect modification of sex on the chronic stress-MetS pathway was observed. CONCLUSIONS: Chronic stress does not explain educational and occupational differences in developing MetS. In fact, individuals with more years of education or higher occupational prestige perceive more chronic stress than their lower SEP counterparts. Further, no difference between males and females was observed regarding the relationship between chronic stress and MetS development. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-022-12684-1.
format Online
Article
Text
id pubmed-8827257
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-88272572022-02-10 Socioeconomic differences in metabolic syndrome development: examining the mediating role of chronic stress using the Lifelines Cohort Study Hoveling, Liza A. Liefbroer, Aart C. Bültmann, Ute Smidt, Nynke BMC Public Health Research BACKGROUND: Metabolic syndrome (MetS) development strongly varies based on individuals’ socioeconomic position (SEP), but to date, no studies have assessed the mediating role of perceived stress from long-term difficulties (chronic stress) in this association. The aim of this study is to examine the mediating role of chronic stress in the associations of the SEP measures education, occupational prestige and income, with MetS development, and whether associations between chronic stress and MetS are moderated by sex. METHODS: We used an adult subsample (n = 53,216) from the Lifelines Cohort Study without MetS at baseline. MetS development was measured 3.9 years after baseline (follow-up), and defined according to National Cholesterol Education Program’s Adult Treatment Panel III (NCEP-ATPIII) criteria. Direct associations between SEP, chronic stress and MetS development were estimated using multivariable logistic and linear regression analyses, and were adjusted for age, sex, the other SEP measures, and time between baseline and follow-up. The mediating percentages of chronic stress explaining the associations between SEP and MetS development were estimated using the Karlson-Holm-Breen method. RESULTS: Upon follow-up, 7.4% of the participants had developed MetS. Years of education and occupational prestige were inversely associated with MetS development. Chronic stress suppressed the association between education and MetS development (5.6%), as well as the association between occupational prestige and MetS development (6.2%). No effect modification of sex on the chronic stress-MetS pathway was observed. CONCLUSIONS: Chronic stress does not explain educational and occupational differences in developing MetS. In fact, individuals with more years of education or higher occupational prestige perceive more chronic stress than their lower SEP counterparts. Further, no difference between males and females was observed regarding the relationship between chronic stress and MetS development. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-022-12684-1. BioMed Central 2022-02-08 /pmc/articles/PMC8827257/ /pubmed/35135520 http://dx.doi.org/10.1186/s12889-022-12684-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Hoveling, Liza A.
Liefbroer, Aart C.
Bültmann, Ute
Smidt, Nynke
Socioeconomic differences in metabolic syndrome development: examining the mediating role of chronic stress using the Lifelines Cohort Study
title Socioeconomic differences in metabolic syndrome development: examining the mediating role of chronic stress using the Lifelines Cohort Study
title_full Socioeconomic differences in metabolic syndrome development: examining the mediating role of chronic stress using the Lifelines Cohort Study
title_fullStr Socioeconomic differences in metabolic syndrome development: examining the mediating role of chronic stress using the Lifelines Cohort Study
title_full_unstemmed Socioeconomic differences in metabolic syndrome development: examining the mediating role of chronic stress using the Lifelines Cohort Study
title_short Socioeconomic differences in metabolic syndrome development: examining the mediating role of chronic stress using the Lifelines Cohort Study
title_sort socioeconomic differences in metabolic syndrome development: examining the mediating role of chronic stress using the lifelines cohort study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827257/
https://www.ncbi.nlm.nih.gov/pubmed/35135520
http://dx.doi.org/10.1186/s12889-022-12684-1
work_keys_str_mv AT hovelinglizaa socioeconomicdifferencesinmetabolicsyndromedevelopmentexaminingthemediatingroleofchronicstressusingthelifelinescohortstudy
AT liefbroeraartc socioeconomicdifferencesinmetabolicsyndromedevelopmentexaminingthemediatingroleofchronicstressusingthelifelinescohortstudy
AT bultmannute socioeconomicdifferencesinmetabolicsyndromedevelopmentexaminingthemediatingroleofchronicstressusingthelifelinescohortstudy
AT smidtnynke socioeconomicdifferencesinmetabolicsyndromedevelopmentexaminingthemediatingroleofchronicstressusingthelifelinescohortstudy