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Synthesis of aromatic lactone analogues of Lipoxin A4

OBJECTIVE: Synthesis of novel aromatic Lipoxin A4 lactone analogues. RESULTS: Novel para-substituted aromatic lactone analogues of Lipoxin A4 have been synthesized in a convergent manner with six steps in the longest linear sequence in 12–13% yields, employing 2-deoxy-d-ribose as a chiral pool start...

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Detalles Bibliográficos
Autores principales: Ismael, Aya, Zeeshan, Muhammad, Hansen, Jørn H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827294/
https://www.ncbi.nlm.nih.gov/pubmed/35139886
http://dx.doi.org/10.1186/s13104-022-05917-4