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BMP7 increases protein synthesis in SW1353 cells and determines rRNA levels in a NKX3-2-dependent manner

BMP7 is a morphogen capable of counteracting the OA chondrocyte hypertrophic phenotype via NKX3-2. NKX3-2 represses expression of RUNX2, an important transcription factor for chondrocyte hypertrophy. Since RUNX2 has previously been described as an inhibitor for 47S pre-rRNA transcription, we hypothe...

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Detalles Bibliográficos
Autores principales:	Ripmeester, Ellen G. J., Welting, Tim J. M., van den Akker, Guus G. H., Surtel, Don A. M., Steijns, Jessica S. J., Cremers, Andy, van Rhijn, Lodewijk W., Caron, Marjolein M. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827423/ https://www.ncbi.nlm.nih.gov/pubmed/35139106 http://dx.doi.org/10.1371/journal.pone.0263430

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