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A high-throughput method to deliver targeted optogenetic stimulation to moving C. elegans populations

We present a high-throughput optogenetic illumination system capable of simultaneous closed-loop light delivery to specified targets in populations of moving Caenorhabditis elegans. The instrument addresses three technical challenges: It delivers targeted illumination to specified regions of the ani...

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Detalles Bibliográficos
Autores principales: Liu, Mochi, Kumar, Sandeep, Sharma, Anuj K., Leifer, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827482/
https://www.ncbi.nlm.nih.gov/pubmed/35089912
http://dx.doi.org/10.1371/journal.pbio.3001524