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13109 Phosphorylation state of Myristoylated Alanine-Rich C-Kinase Substrate Effector Domain mimetics determines its cytotoxicity in glioblastoma and macrophage model

ABSTRACT IMPACT: This study provides insight into how MED2 impacts the immune cells surrounding glioblastoma that help it to grow and spread; having a more complete understanding of how MED2 works will help us better develop therapies that may one day enter the clinic to improve patient outcomes in...

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Detalles Bibliográficos
Autores principales: Alrefai, Hasan, Eustace, Nicholas J., Anderson, Joshua C., Hicks, Patricia H., King, Peter H., Willey, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827758/
http://dx.doi.org/10.1017/cts.2021.403