Cargando…

32329 A novel mouse model of Ataxia Telangiectasia for testing small molecule readthrough compounds

ABSTRACT IMPACT: Small molecule readthrough compounds are a promising therapeutic with the potential to overcome nonsense mutations thereby enabling the production of functional ATM protein in patients with Ataxia Telangiectasia OBJECTIVES/GOALS: To generate a novel mouse model of Ataxia-Telangiecta...

Descripción completa

Detalles Bibliográficos
Autor principal: Mathews, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827764/
http://dx.doi.org/10.1017/cts.2021.430

Ejemplares similares