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15727 K(ATP) channel prodrugs as therapeutics for chronic pain and substance abuse disorders

ABSTRACT IMPACT: Pharmacological activation of K(ATP) channels may provide analgesia and attenuate opioid tolerance and withdrawal OBJECTIVES/GOALS: Our long term goal is to develop therapeutics for the treatment of the overuse of opioids. The objective of this application is to test novel K(ATP) ch...

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Detalles Bibliográficos
Autores principales: Doucette, Alexis, Johnson, Kayla, Dosa, Peter I., Klein, Amanda H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827765/
http://dx.doi.org/10.1017/cts.2021.422