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34380 Cadherin complexes recruit PIWIL2 to suppress transposons and pro-tumorigenic transformation

ABSTRACT IMPACT: This study has uncovered a novel surprising mechanism involving the epithelial adherens junctions and transposon regulation that can deepen our understanding of tumorigenesis. OBJECTIVES/GOALS: Recent studies show that genomic instability in 50% of tumors can be attributed to increa...

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Detalles Bibliográficos
Autores principales:	Risner, Alyssa, Nair-Menon, Joyce, McDowell, Colin, Gangaraju, Vamsi, Kourtidis, Antonis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2021
Materias:	Basic Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827795/ http://dx.doi.org/10.1017/cts.2021.432

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