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RNA binding to human METTL3-METTL14 restricts N(6)-deoxyadenosine methylation of DNA in vitro

Methyltransferase like-3 (METTL3) and METTL14 complex transfers a methyl group from S-adenosyl-L-methionine to N(6) amino group of adenosine bases in RNA (m(6)A) and DNA (m(6)dA). Emerging evidence highlights a role of METTL3-METTL14 in the chromatin context, especially in processes where DNA and RN...

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Detalles Bibliográficos
Autores principales:	Qi, Shan, Mota, Javier, Chan, Siu-Hong, Villarreal, Johanna, Dai, Nan, Arya, Shailee, Hromas, Robert A, Rao, Manjeet K, Corrêa Jr, Ivan R, Gupta, Yogesh K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828048/ https://www.ncbi.nlm.nih.gov/pubmed/35060905 http://dx.doi.org/10.7554/eLife.67150

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