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Squidpy: a scalable framework for spatial omics analysis
Spatial omics data are advancing the study of tissue organization and cellular communication at an unprecedented scale. Flexible tools are required to store, integrate and visualize the large diversity of spatial omics data. Here, we present Squidpy, a Python framework that brings together tools fro...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828470/ https://www.ncbi.nlm.nih.gov/pubmed/35102346 http://dx.doi.org/10.1038/s41592-021-01358-2 |
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author | Palla, Giovanni Spitzer, Hannah Klein, Michal Fischer, David Schaar, Anna Christina Kuemmerle, Louis Benedikt Rybakov, Sergei Ibarra, Ignacio L. Holmberg, Olle Virshup, Isaac Lotfollahi, Mohammad Richter, Sabrina Theis, Fabian J. |
author_facet | Palla, Giovanni Spitzer, Hannah Klein, Michal Fischer, David Schaar, Anna Christina Kuemmerle, Louis Benedikt Rybakov, Sergei Ibarra, Ignacio L. Holmberg, Olle Virshup, Isaac Lotfollahi, Mohammad Richter, Sabrina Theis, Fabian J. |
author_sort | Palla, Giovanni |
collection | PubMed |
description | Spatial omics data are advancing the study of tissue organization and cellular communication at an unprecedented scale. Flexible tools are required to store, integrate and visualize the large diversity of spatial omics data. Here, we present Squidpy, a Python framework that brings together tools from omics and image analysis to enable scalable description of spatial molecular data, such as transcriptome or multivariate proteins. Squidpy provides efficient infrastructure and numerous analysis methods that allow to efficiently store, manipulate and interactively visualize spatial omics data. Squidpy is extensible and can be interfaced with a variety of already existing libraries for the scalable analysis of spatial omics data. |
format | Online Article Text |
id | pubmed-8828470 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group US |
record_format | MEDLINE/PubMed |
spelling | pubmed-88284702022-02-22 Squidpy: a scalable framework for spatial omics analysis Palla, Giovanni Spitzer, Hannah Klein, Michal Fischer, David Schaar, Anna Christina Kuemmerle, Louis Benedikt Rybakov, Sergei Ibarra, Ignacio L. Holmberg, Olle Virshup, Isaac Lotfollahi, Mohammad Richter, Sabrina Theis, Fabian J. Nat Methods Article Spatial omics data are advancing the study of tissue organization and cellular communication at an unprecedented scale. Flexible tools are required to store, integrate and visualize the large diversity of spatial omics data. Here, we present Squidpy, a Python framework that brings together tools from omics and image analysis to enable scalable description of spatial molecular data, such as transcriptome or multivariate proteins. Squidpy provides efficient infrastructure and numerous analysis methods that allow to efficiently store, manipulate and interactively visualize spatial omics data. Squidpy is extensible and can be interfaced with a variety of already existing libraries for the scalable analysis of spatial omics data. Nature Publishing Group US 2022-01-31 2022 /pmc/articles/PMC8828470/ /pubmed/35102346 http://dx.doi.org/10.1038/s41592-021-01358-2 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Palla, Giovanni Spitzer, Hannah Klein, Michal Fischer, David Schaar, Anna Christina Kuemmerle, Louis Benedikt Rybakov, Sergei Ibarra, Ignacio L. Holmberg, Olle Virshup, Isaac Lotfollahi, Mohammad Richter, Sabrina Theis, Fabian J. Squidpy: a scalable framework for spatial omics analysis |
title | Squidpy: a scalable framework for spatial omics analysis |
title_full | Squidpy: a scalable framework for spatial omics analysis |
title_fullStr | Squidpy: a scalable framework for spatial omics analysis |
title_full_unstemmed | Squidpy: a scalable framework for spatial omics analysis |
title_short | Squidpy: a scalable framework for spatial omics analysis |
title_sort | squidpy: a scalable framework for spatial omics analysis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828470/ https://www.ncbi.nlm.nih.gov/pubmed/35102346 http://dx.doi.org/10.1038/s41592-021-01358-2 |
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