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Multi-layered regulation of neuroectoderm differentiation by retinoic acid in a primitive streak-like context

The formation of the primitive streak (PS) and the subsequent induction of neuroectoderm are hallmarks of gastrulation. Combining an in vitro reconstitution of this process based on mouse embryonic stem cells (mESCs) with a collection of knockouts in reporter mESC lines, we identified retinoic acid...

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Detalles Bibliográficos
Autores principales: Russo, Luigi, Sladitschek, Hanna L., Neveu, Pierre A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828549/
https://www.ncbi.nlm.nih.gov/pubmed/35063128
http://dx.doi.org/10.1016/j.stemcr.2021.12.014