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RNF43/ZNRF3 negatively regulates taste tissue homeostasis and positively regulates dorsal lingual epithelial tissue homeostasis

Taste bud cells are renewed throughout life in a process requiring innervation. Recently, we reported that R-spondin substitutes for neuronal input for taste cell regeneration. R-spondin amplifies WNT signaling by interacting with stem-cell-expressed E3 ubiquitin ligases RNF43/ZNRF3 (negative regula...

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Detalles Bibliográficos
Autores principales:	Lu, Chanyi, Lin, Xiaoli, Yamashita, Jumpei, Xi, Ranhui, Zhou, Minliang, Zhang, Yali V., Wang, Hong, Margolskee, Robert F., Koo, Bon-Kyoung, Clevers, Hans, Matsumoto, Ichiro, Jiang, Peihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828551/ https://www.ncbi.nlm.nih.gov/pubmed/34995498 http://dx.doi.org/10.1016/j.stemcr.2021.12.002

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