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PAX6-positive microglia evolve locally in hiPSC-derived ocular organoids
Microglia are the resident immune cells of the central nervous system (CNS). They govern the immunogenicity of the retina, which is considered to be part of the CNS; however, it is not known how microglia develop in the eye. Here, we studied human-induced pluripotent stem cells (hiPSCs) that had bee...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828554/ https://www.ncbi.nlm.nih.gov/pubmed/35030319 http://dx.doi.org/10.1016/j.stemcr.2021.12.009 |