PAX6-positive microglia evolve locally in hiPSC-derived ocular organoids

Microglia are the resident immune cells of the central nervous system (CNS). They govern the immunogenicity of the retina, which is considered to be part of the CNS; however, it is not known how microglia develop in the eye. Here, we studied human-induced pluripotent stem cells (hiPSCs) that had bee...

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Detalles Bibliográficos
Autores principales: Shiraki, Nobuhiko, Maruyama, Kazuichi, Hayashi, Ryuhei, Oguchi, Akiko, Murakawa, Yasuhiro, Katayama, Tomohiko, Takigawa, Toru, Sakimoto, Susumu, Quantock, Andrew J., Tsujikawa, Motokazu, Nishida, Kohji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828554/
https://www.ncbi.nlm.nih.gov/pubmed/35030319
http://dx.doi.org/10.1016/j.stemcr.2021.12.009

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