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CA9-Related Acidic Microenvironment Mediates CD8+ T Cell Related Immunosuppression in Pancreatic Cancer

PURPOSE: This study aims to integrate pancreatic cancer TCGA, GEO, and single-cell RNA-sequencing (scRNA-seq) datasets, and explore the potential prognostic markers and underlying mechanisms of the immune microenvironment of pancreatic cancer through bioinformatics methods, in vitro and in vivo assa...

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Detalles Bibliográficos
Autores principales:	Yin, Lingdi, Lu, Yichao, Cao, Cheng, Lu, Zipeng, Wei, Jishu, Zhu, Xiaole, Chen, Jianmin, Guo, Feng, Tu, Min, Xi, Chunhua, Zhang, Kai, Wu, Junli, Gao, Wentao, Jiang, Kuirong, Miao, Yi, Li, Qiang, Peng, Yunpeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828571/ https://www.ncbi.nlm.nih.gov/pubmed/35155218 http://dx.doi.org/10.3389/fonc.2021.832315

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