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Histopathological changes of the spinal cord and motor neuron dynamics in SOD1 Tg mice

We analyzed the histopathological changes and the number of motor neurons (MNs) in the lumbar spinal cord of Cu/Zn superoxide dismutase transgenic (SOD1(G93A)Tg) mice, which are frequently used as a disease model of amyotrophic lateral sclerosis (ALS). In SOD1(G93A)Tg mice, hyaline inclusions and fo...

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Detalles Bibliográficos
Autores principales: Tanaka, Masaharu, Homma, Kengo, Soejima, Aki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828614/
https://www.ncbi.nlm.nih.gov/pubmed/35221507
http://dx.doi.org/10.1293/tox.2021-0056