Cargando…
Histopathological changes of the spinal cord and motor neuron dynamics in SOD1 Tg mice
We analyzed the histopathological changes and the number of motor neurons (MNs) in the lumbar spinal cord of Cu/Zn superoxide dismutase transgenic (SOD1(G93A)Tg) mice, which are frequently used as a disease model of amyotrophic lateral sclerosis (ALS). In SOD1(G93A)Tg mice, hyaline inclusions and fo...
Autores principales: | Tanaka, Masaharu, Homma, Kengo, Soejima, Aki |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese Society of Toxicologic Pathology
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828614/ https://www.ncbi.nlm.nih.gov/pubmed/35221507 http://dx.doi.org/10.1293/tox.2021-0056 |
Ejemplares similares
-
Aldehyde Dehydrogenases 1A2 Expression and Distribution are Potentially Associated with Neuron Death in Spinal Cord of Tg(SOD1*G93A)1Gur Mice
por: Liang, Huiting, et al.
Publicado: (2017) -
Changes in the Expression of FUS/TLS in Spinal Cords of SOD1 G93A Transgenic Mice and Correlation with Motor-Neuron Degeneration
por: Li, Jiao, et al.
Publicado: (2016) -
RNA-Seq Profiling of Spinal Cord Motor Neurons from a Presymptomatic SOD1 ALS Mouse
por: Bandyopadhyay, Urmi, et al.
Publicado: (2013) -
Trophic and proliferative effects of Shh on motor neurons in embryonic spinal cord culture from wildtype and G93A SOD1 mice
por: Ma, Xiaoxing, et al.
Publicado: (2013) -
The Timing and Extent of Motor Neuron Vulnerability in ALS Correlates with Accumulation of Misfolded SOD1 Protein in the Cortex and in the Spinal Cord
por: Genc, Baris, et al.
Publicado: (2020)