Full efficacy and long-term immunogenicity induced by the SARS-CoV-2 vaccine candidate MVA-CoV2-S in mice

Two doses of the MVA-CoV2-S vaccine candidate expressing the SARS-CoV-2 spike (S) protein protected K18-hACE2 transgenic mice from a lethal dose of SARS-CoV-2. This vaccination regimen prevented virus replication in the lungs, reduced lung pathology, and diminished levels of pro-inflammatory cytokin...

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Detalles Bibliográficos
Autores principales: Lázaro-Frías, Adrián, Pérez, Patricia, Zamora, Carmen, Sánchez-Cordón, Pedro J., Guzmán, María, Luczkowiak, Joanna, Delgado, Rafael, Casasnovas, José M., Esteban, Mariano, García-Arriaza, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828760/
https://www.ncbi.nlm.nih.gov/pubmed/35140227
http://dx.doi.org/10.1038/s41541-022-00440-w

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