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Co-occurrence CDK4/6 amplification serves as biomarkers of de novo EGFR TKI resistance in sensitizing EGFR mutation non-small cell lung cancer

Despite the development of predictive biomarkers to shape treatment paradigms and outcomes, de novo EGFR TKI resistance advanced non-small cell lung cancer (NSCLC) remains an issue of concern. We explored clinical factors in 332 advanced NSCLC who received EGFR TKI and molecular characteristics thro...

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Detalles Bibliográficos
Autores principales:	Sitthideatphaiboon, Piyada, Teerapakpinyo, Chinachote, Korphaisarn, Krittiya, Leelayuwatanakul, Nophol, Pornpatrananrak, Nopporn, Poungvarin, Naravat, Chantranuwat, Poonchavist, Shuangshoti, Shanop, Aporntewan, Chatchawit, Chintanapakdee, Wariya, Sriuranpong, Virote, Vinayanuwattikun, Chanida
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828869/ https://www.ncbi.nlm.nih.gov/pubmed/35140316 http://dx.doi.org/10.1038/s41598-022-06239-y

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