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Mycobacterium vaccae immunization in rats ameliorates features of age-associated microglia activation in the amygdala and hippocampus
Aging and reduced exposure to environmental microbes can both potentiate neuroinflammatory responses. Prior studies indicate that immunization with the immunoregulatory and anti-inflammatory bacterium, Mycobacterium vaccae (M. vaccae), in aged rats limits neuroimmune activation and cognitive impairm...
Autores principales: | Sanchez, Kevin, Darling, Jeffrey S., Kakkar, Reha, Wu, Sienna L., Zentay, Andrew, Lowry, Christopher A., Fonken, Laura K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828872/ https://www.ncbi.nlm.nih.gov/pubmed/35140249 http://dx.doi.org/10.1038/s41598-022-05275-y |
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