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Mycobacterium vaccae immunization in rats ameliorates features of age-associated microglia activation in the amygdala and hippocampus

Aging and reduced exposure to environmental microbes can both potentiate neuroinflammatory responses. Prior studies indicate that immunization with the immunoregulatory and anti-inflammatory bacterium, Mycobacterium vaccae (M. vaccae), in aged rats limits neuroimmune activation and cognitive impairm...

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Detalles Bibliográficos
Autores principales: Sanchez, Kevin, Darling, Jeffrey S., Kakkar, Reha, Wu, Sienna L., Zentay, Andrew, Lowry, Christopher A., Fonken, Laura K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828872/
https://www.ncbi.nlm.nih.gov/pubmed/35140249
http://dx.doi.org/10.1038/s41598-022-05275-y

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