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Killer Cell Immunoglobulin-Like Receptor Haplotype B Modulates Susceptibility to EBV-Associated Classic Hodgkin Lymphoma

Tumor cells of classic Hodgkin lymphoma (cHL) are derived from antigen presenting B cells that are infected by Epstein Barr virus (EBV) in ~30% of patients. Polymorphic Killer cell immunoglobulin-like receptors (KIRs) expressed on NK cells interact with human leukocyte antigen (HLA) class I and play...

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Detalles Bibliográficos
Autores principales: Jiang, Peijia, Nolte, Ilja M., Hepkema, Bouke G., Stulp, Marijke, van den Berg, Anke, Diepstra, Arjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828906/
https://www.ncbi.nlm.nih.gov/pubmed/35154153
http://dx.doi.org/10.3389/fimmu.2022.829943