Cargando…
An unusual pigmented tonsil neoplasm presenting to Head & Neck Clinic: a case report and literature review of primary tonsillar malignant mucosal melanoma
Primary mucosal melanoma of the tonsil is rare, with 27 reported cases. Careful diagnosis is necessary, as the tonsil is more often a site of metastatic melanoma from a cutaneous primary tumour. In this report, we present a case of primary right tonsillar mucosal melanoma with widespread metastasis...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829020/ https://www.ncbi.nlm.nih.gov/pubmed/35154640 http://dx.doi.org/10.1093/jscr/rjac022 |
_version_ | 1784647974781976576 |
---|---|
author | Rae, Pete J Bates, James E H M Fraser, Lisa R |
author_facet | Rae, Pete J Bates, James E H M Fraser, Lisa R |
author_sort | Rae, Pete J |
collection | PubMed |
description | Primary mucosal melanoma of the tonsil is rare, with 27 reported cases. Careful diagnosis is necessary, as the tonsil is more often a site of metastatic melanoma from a cutaneous primary tumour. In this report, we present a case of primary right tonsillar mucosal melanoma with widespread metastasis in a 31-year-old man who presented with a 3-month history of enlarging neck lumps. On examination, he had cervical lymphadenopathy and a pigmented, vascular lesion of his right tonsil, which was diagnosed as melanoma following investigation. He had widespread metastases upon presentation, and is currently undergoing palliative immunotherapy. Owing to the aggressive behaviour, late presentations and lack of effective treatment to cure mucosal melanomas, they have a poor prognosis. Treatment involves wide local excision in local disease, and immunotherapy as the first-line for metastatic disease. |
format | Online Article Text |
id | pubmed-8829020 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-88290202022-02-10 An unusual pigmented tonsil neoplasm presenting to Head & Neck Clinic: a case report and literature review of primary tonsillar malignant mucosal melanoma Rae, Pete J Bates, James E H M Fraser, Lisa R J Surg Case Rep Case Report Primary mucosal melanoma of the tonsil is rare, with 27 reported cases. Careful diagnosis is necessary, as the tonsil is more often a site of metastatic melanoma from a cutaneous primary tumour. In this report, we present a case of primary right tonsillar mucosal melanoma with widespread metastasis in a 31-year-old man who presented with a 3-month history of enlarging neck lumps. On examination, he had cervical lymphadenopathy and a pigmented, vascular lesion of his right tonsil, which was diagnosed as melanoma following investigation. He had widespread metastases upon presentation, and is currently undergoing palliative immunotherapy. Owing to the aggressive behaviour, late presentations and lack of effective treatment to cure mucosal melanomas, they have a poor prognosis. Treatment involves wide local excision in local disease, and immunotherapy as the first-line for metastatic disease. Oxford University Press 2022-02-09 /pmc/articles/PMC8829020/ /pubmed/35154640 http://dx.doi.org/10.1093/jscr/rjac022 Text en Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2022. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Rae, Pete J Bates, James E H M Fraser, Lisa R An unusual pigmented tonsil neoplasm presenting to Head & Neck Clinic: a case report and literature review of primary tonsillar malignant mucosal melanoma |
title | An unusual pigmented tonsil neoplasm presenting to Head & Neck Clinic: a case report and literature review of primary tonsillar malignant mucosal melanoma |
title_full | An unusual pigmented tonsil neoplasm presenting to Head & Neck Clinic: a case report and literature review of primary tonsillar malignant mucosal melanoma |
title_fullStr | An unusual pigmented tonsil neoplasm presenting to Head & Neck Clinic: a case report and literature review of primary tonsillar malignant mucosal melanoma |
title_full_unstemmed | An unusual pigmented tonsil neoplasm presenting to Head & Neck Clinic: a case report and literature review of primary tonsillar malignant mucosal melanoma |
title_short | An unusual pigmented tonsil neoplasm presenting to Head & Neck Clinic: a case report and literature review of primary tonsillar malignant mucosal melanoma |
title_sort | unusual pigmented tonsil neoplasm presenting to head & neck clinic: a case report and literature review of primary tonsillar malignant mucosal melanoma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829020/ https://www.ncbi.nlm.nih.gov/pubmed/35154640 http://dx.doi.org/10.1093/jscr/rjac022 |
work_keys_str_mv | AT raepetej anunusualpigmentedtonsilneoplasmpresentingtoheadneckclinicacasereportandliteraturereviewofprimarytonsillarmalignantmucosalmelanoma AT batesjamesehm anunusualpigmentedtonsilneoplasmpresentingtoheadneckclinicacasereportandliteraturereviewofprimarytonsillarmalignantmucosalmelanoma AT fraserlisar anunusualpigmentedtonsilneoplasmpresentingtoheadneckclinicacasereportandliteraturereviewofprimarytonsillarmalignantmucosalmelanoma AT raepetej unusualpigmentedtonsilneoplasmpresentingtoheadneckclinicacasereportandliteraturereviewofprimarytonsillarmalignantmucosalmelanoma AT batesjamesehm unusualpigmentedtonsilneoplasmpresentingtoheadneckclinicacasereportandliteraturereviewofprimarytonsillarmalignantmucosalmelanoma AT fraserlisar unusualpigmentedtonsilneoplasmpresentingtoheadneckclinicacasereportandliteraturereviewofprimarytonsillarmalignantmucosalmelanoma |