Elevated blood monocyte counts in alcohol‐associated hepatitis

In this retrospective study of 164 patients with alcohol‐associated hepatitis, we find that the mean absolute monocyte count is 0.95 thousand cells/L, which is significantly higher than the upper limit of normal (0.80 thousand cells/μL) (P < 0.0001). Monocyte count is correlated with disease seve...

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Detalles Bibliográficos
Autores principales: Voss, Jordan K., Li, Zhuan, Weinman, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Publishing Asia Pty Ltd 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829102/
https://www.ncbi.nlm.nih.gov/pubmed/35155825
http://dx.doi.org/10.1002/jgh3.12707
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author Voss, Jordan K.
Li, Zhuan
Weinman, Steven A.
author_facet Voss, Jordan K.
Li, Zhuan
Weinman, Steven A.
author_sort Voss, Jordan K.
collection PubMed
description In this retrospective study of 164 patients with alcohol‐associated hepatitis, we find that the mean absolute monocyte count is 0.95 thousand cells/L, which is significantly higher than the upper limit of normal (0.80 thousand cells/μL) (P < 0.0001). Monocyte count is correlated with disease severity as measured by MELD score (R = 0.400, P < 0.0001) and Maddrey discriminant function (R = 0.330, P < 0.0001).[Image: see text]
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spelling pubmed-88291022022-02-11 Elevated blood monocyte counts in alcohol‐associated hepatitis Voss, Jordan K. Li, Zhuan Weinman, Steven A. JGH Open Brief Report In this retrospective study of 164 patients with alcohol‐associated hepatitis, we find that the mean absolute monocyte count is 0.95 thousand cells/L, which is significantly higher than the upper limit of normal (0.80 thousand cells/μL) (P < 0.0001). Monocyte count is correlated with disease severity as measured by MELD score (R = 0.400, P < 0.0001) and Maddrey discriminant function (R = 0.330, P < 0.0001).[Image: see text] Wiley Publishing Asia Pty Ltd 2022-01-27 /pmc/articles/PMC8829102/ /pubmed/35155825 http://dx.doi.org/10.1002/jgh3.12707 Text en © 2022 The Authors. JGH Open published by Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Brief Report
Voss, Jordan K.
Li, Zhuan
Weinman, Steven A.
Elevated blood monocyte counts in alcohol‐associated hepatitis
title Elevated blood monocyte counts in alcohol‐associated hepatitis
title_full Elevated blood monocyte counts in alcohol‐associated hepatitis
title_fullStr Elevated blood monocyte counts in alcohol‐associated hepatitis
title_full_unstemmed Elevated blood monocyte counts in alcohol‐associated hepatitis
title_short Elevated blood monocyte counts in alcohol‐associated hepatitis
title_sort elevated blood monocyte counts in alcohol‐associated hepatitis
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829102/
https://www.ncbi.nlm.nih.gov/pubmed/35155825
http://dx.doi.org/10.1002/jgh3.12707
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