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Bringing social context into global biomedical HIV cure-related research: An urgent call to action

Advances in science have ushered in a wave of new potential curative and control strategies for HIV that could eliminate the current requirement for life-long antiretroviral therapy (ART) for people living with HIV (PLWH). In this article, we argue that it is critical to consider social contexts in...

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Detalles Bibliográficos
Autores principales: Miall, Annie, McLellan, Rio, Dong, Krista, Ndung'u, Thumbi, Saberi, Parya, Sauceda, John A., Dubé, Karine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829132/
https://www.ncbi.nlm.nih.gov/pubmed/35169489
http://dx.doi.org/10.1016/j.jve.2021.100062
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author Miall, Annie
McLellan, Rio
Dong, Krista
Ndung'u, Thumbi
Saberi, Parya
Sauceda, John A.
Dubé, Karine
author_facet Miall, Annie
McLellan, Rio
Dong, Krista
Ndung'u, Thumbi
Saberi, Parya
Sauceda, John A.
Dubé, Karine
author_sort Miall, Annie
collection PubMed
description Advances in science have ushered in a wave of new potential curative and control strategies for HIV that could eliminate the current requirement for life-long antiretroviral therapy (ART) for people living with HIV (PLWH). In this article, we argue that it is critical to consider social contexts in the development of HIV cure trial protocols. The biological and behavioral risk factors for HIV acquisition by study participants are inseparable from the social context in which these participants live. The article discusses an example of a cohort established to further HIV cure research that included social context, called the FRESH Acute HIV study, which combines a sociostructural intervention while conducting HIV prevention, treatment and cure-related research in Durban, South Africa. We make an urgent call to action to include sociobehavioral components as instrumental in future HIV cure trials in global context.
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spelling pubmed-88291322022-02-14 Bringing social context into global biomedical HIV cure-related research: An urgent call to action Miall, Annie McLellan, Rio Dong, Krista Ndung'u, Thumbi Saberi, Parya Sauceda, John A. Dubé, Karine J Virus Erad Letters to the Editor Advances in science have ushered in a wave of new potential curative and control strategies for HIV that could eliminate the current requirement for life-long antiretroviral therapy (ART) for people living with HIV (PLWH). In this article, we argue that it is critical to consider social contexts in the development of HIV cure trial protocols. The biological and behavioral risk factors for HIV acquisition by study participants are inseparable from the social context in which these participants live. The article discusses an example of a cohort established to further HIV cure research that included social context, called the FRESH Acute HIV study, which combines a sociostructural intervention while conducting HIV prevention, treatment and cure-related research in Durban, South Africa. We make an urgent call to action to include sociobehavioral components as instrumental in future HIV cure trials in global context. Elsevier 2021-12-28 /pmc/articles/PMC8829132/ /pubmed/35169489 http://dx.doi.org/10.1016/j.jve.2021.100062 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Letters to the Editor
Miall, Annie
McLellan, Rio
Dong, Krista
Ndung'u, Thumbi
Saberi, Parya
Sauceda, John A.
Dubé, Karine
Bringing social context into global biomedical HIV cure-related research: An urgent call to action
title Bringing social context into global biomedical HIV cure-related research: An urgent call to action
title_full Bringing social context into global biomedical HIV cure-related research: An urgent call to action
title_fullStr Bringing social context into global biomedical HIV cure-related research: An urgent call to action
title_full_unstemmed Bringing social context into global biomedical HIV cure-related research: An urgent call to action
title_short Bringing social context into global biomedical HIV cure-related research: An urgent call to action
title_sort bringing social context into global biomedical hiv cure-related research: an urgent call to action
topic Letters to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829132/
https://www.ncbi.nlm.nih.gov/pubmed/35169489
http://dx.doi.org/10.1016/j.jve.2021.100062
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