Compromised Astrocyte Swelling/Volume Regulation in the Hippocampus of the Triple Transgenic Mouse Model of Alzheimer’s Disease

In this study, we aimed to disclose the impact of amyloid-β toxicity and tau pathology on astrocyte swelling, their volume recovery and extracellular space (ECS) diffusion parameters, namely volume fraction (α) and tortuosity (λ), in a triple transgenic mouse model of Alzheimer’s disease (3xTg-AD)....

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Detalles Bibliográficos
Autores principales: Tureckova, Jana, Kamenicka, Monika, Kolenicova, Denisa, Filipi, Tereza, Hermanova, Zuzana, Kriska, Jan, Meszarosova, Lenka, Pukajova, Barbora, Valihrach, Lukas, Androvic, Peter, Zucha, Daniel, Chmelova, Martina, Vargova, Lydia, Anderova, Miroslava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829436/
https://www.ncbi.nlm.nih.gov/pubmed/35153718
http://dx.doi.org/10.3389/fnagi.2021.783120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829436/
https://www.ncbi.nlm.nih.gov/pubmed/35153718
http://dx.doi.org/10.3389/fnagi.2021.783120

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