Inflammatory-miR-301a circuitry drives mTOR and Stat3-dependent PSC activation in chronic pancreatitis and PanIN

Activated pancreatic stellate cells (PSCs) are the main cells involved in chronic pancreatitis and pancreatic intraepithelial neoplasia lesion (PanIN). Fine-tuning the precise molecular targets in PSC activation might help the development of PSC-specific therapeutic strategies to tackle progression...

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Detalles Bibliográficos
Autores principales: Li, Fugui, Wang, Miaomiao, Li, Xun, Long, Yihao, Chen, Kaizhao, Wang, Xinjie, Zhong, Mingtian, Cheng, Weimin, Tian, Xuemei, Wang, Ping, Ji, Mingfang, Ma, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829454/
https://www.ncbi.nlm.nih.gov/pubmed/35211358
http://dx.doi.org/10.1016/j.omtn.2022.01.011

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