A novel DNA aptamer targeting lung cancer stem cells exerts a therapeutic effect by binding and neutralizing Annexin A2

Cancer remains one of the leading causes of death worldwide. Cancer stem cells (CSCs) are the underlying reason for tumor recurrence, progression, and therapeutic resistance. Aptamers are synthetic single-stranded oligonucleotides that can specifically bind to various molecular targets. Here, we aim...

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Detalles Bibliográficos
Autores principales: Wu, Yi-Ying, Hsieh, I-Shan, Tung, Chia-Hao, Weng, Chen-Hsun, Wu, Jia-En, Yu, Jau-Song, Hong, Tse-Ming, Chen, Yuh-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829491/
https://www.ncbi.nlm.nih.gov/pubmed/35211356
http://dx.doi.org/10.1016/j.omtn.2022.01.012

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