Cargando…

Structural Comparison and Drug Screening of Spike Proteins of Ten SARS-CoV-2 Variants

SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) has evolved many variants with stronger infectivity and immune evasion than the original strain, including Alpha, Beta, Gamma, Delta, Epsilon, Kappa, Iota, Lambda, and 21H strains. Amino acid mutations are enriched in the spike protein of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Qiangzhen, Jian, Xuemin, Syed, Ali Alamdar Shah, Fahira, Aamir, Zheng, Chenxiang, Zhu, Zijia, Wang, Ke, Zhang, Jinmai, Wen, Yanqin, Li, Zhiqiang, Pan, Dun, Lu, Tingting, Wang, Zhuo, Shi, Yongyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAAS 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829538/ https://www.ncbi.nlm.nih.gov/pubmed/35198984 http://dx.doi.org/10.34133/2022/9781758

Ejemplares similares

Structural Analysis of the SARS-CoV-2 Omicron Variant Proteins
por: Yang, Qiangzhen, et al.
Publicado: (2021)

The Relationship between Alcohol Consumption and Gout: A Mendelian Randomization Study
por: Syed, Ali Alamdar Shah, et al.
Publicado: (2022)

Chimeric vaccine design against the epidemic Langya Henipavirus using immunoinformatics and validation via immune simulation approaches
por: Fahira, Aamir, et al.
Publicado: (2023)

Highly accurate protein structure prediction and drug screen of monkeypox virus proteome
por: Yang, Qiangzhen, et al.
Publicado: (2023)

Integrative omics analysis reveals effective stratification and potential prognosis markers of pan-gastrointestinal cancers
por: Jiangzhou, Huiting, et al.
Publicado: (2021)

Correction to: Genetic risk of clozapine-induced leukopenia and neutropenia: a genome-wide association study
por: Chen, Jianhua, et al.
Publicado: (2021)

Genetic risk of clozapine-induced leukopenia and neutropenia: a genome-wide association study
por: Chen, Jianhua, et al.
Publicado: (2021)

The Potential Effect of Aberrant Testosterone Levels on Common Diseases: A Mendelian Randomization Study
por: Syed, Ali Alamdar Shah, et al.
Publicado: (2020)

Mechanistic Modeling of Gene Regulation and Metabolism Identifies Potential Targets for Hepatocellular Carcinoma
por: Sun, Renliang, et al.
Publicado: (2020)

Renal hypouricemia caused by novel compound heterozygous mutations in the SLC22A12 gene: a case report with literature review
por: Zhou, Zhaowei, et al.
Publicado: (2018)

Integrative Genomic Analysis of m6a-SNPs Identifies Potential Functional Variants Associated with Alzheimer’s Disease
por: Jan, Syed Mansoor, et al.
Publicado: (2023)

A Polynesian-specific copy number variant encompassing the MICA gene associates with gout
por: Wang, Ke, et al.
Publicado: (2022)

STRsearch: a new pipeline for targeted profiling of short tandem repeats in massively parallel sequencing data
por: Wang, Dong, et al.
Publicado: (2020)

Ten emerging SARS-CoV-2 spike variants exhibit variable infectivity, animal tropism, and antibody neutralization
por: Zhang, Li, et al.
Publicado: (2021)

Rare and common variants analysis of the EMB gene in patients with schizophrenia
por: Zhou, Juan, et al.
Publicado: (2020)

Identification of rare and common variants in BNIP3L: a schizophrenia susceptibility gene
por: Zhou, Juan, et al.
Publicado: (2020)

Performance comparison of four types of target enrichment baits for exome DNA sequencing
por: Zhou, Juan, et al.
Publicado: (2021)

Correction to: Performance comparison of four types of target enrichment baits for exome DNA sequencing
por: Zhou, Juan, et al.
Publicado: (2023)

Multi-omics characterization reveals the pathogenesis of liver focal nodular hyperplasia
por: Liu, Yuming, et al.
Publicado: (2022)

Polymorphism of the PPARD Gene and Dynamic Balance Performance in Han Chinese Children
por: Cao, Yixuan, et al.
Publicado: (2019)

VariFAST: a variant filter by automated scoring based on tagged-signatures
por: Zhang, Hang, et al.
Publicado: (2019)

Testosterone in Female Depression: A Meta-Analysis and Mendelian Randomization Study
por: Maharjan, Dhruba Tara, et al.
Publicado: (2021)

Characterization and Function of Glycans on the Spike Proteins of SARS-CoV-2 Variants of Concern
por: Zheng, Luping, et al.
Publicado: (2022)

Common variants in the SLC28A2 gene are associated with serum uric acid level and hyperuricemia and gout in Han Chinese
por: Zhou, Zhaowei, et al.
Publicado: (2019)

Novel VAC14 variants identified in two Chinese siblings with childhood‐onset striatonigral degeneration
por: Liao, Shuang, et al.
Publicado: (2019)

Takotsubo cardiomyopathy: ten year experience at a tertiary care hospital in Pakistan
por: Laghari, Abid Hussain, et al.
Publicado: (2014)

Peripartum cardiomyopathy: ten year experience at a tertiary care hospital in Pakistan
por: Laghari, Abid Hussain, et al.
Publicado: (2013)

Fine‐mapping of ZDHHC2 identifies risk variants for schizophrenia in the Han Chinese population
por: Zhang, Han, et al.
Publicado: (2020)

Delta spike P681R mutation enhances SARS-CoV-2 fitness over Alpha variant
por: Liu, Yang, et al.
Publicado: (2021)

Delta spike P681R mutation enhances SARS-CoV-2 fitness over Alpha variant
por: Liu, Yang, et al.
Publicado: (2022)

Amplicon targeted resequencing for SLC2A9 and SLC22A12 identified novel mutations in hypouricemia subjects
por: Zhou, Zhaowei, et al.
Publicado: (2019)

Common variants at ten loci influence myocardial repolarization: the QTGEN consortium
por: Newton-Cheh, Christopher, et al.
Publicado: (2009)

SLC39A8 is a risk factor for schizophrenia in Uygur Chinese: a case-control study
por: Jian, Xuemin, et al.
Publicado: (2019)

Epitope mapping of spike identifies variant-resistant antibodies
por: Flemming, Alexandra
Publicado: (2021)

Emergence of Genomic Diversity in the Spike Protein of the “Omicron” Variant
por: Basak, Surajit, et al.
Publicado: (2023)

Association Analysis Between Common Variants of the TRPM1 Gene and Three Mental Disorders in the Han Chinese Population
por: Ma, Chuanchuan, et al.
Publicado: (2020)

A review on literature of Islamic microfinance from 2010-2020: lesson for practitioners and future directions
por: Rohman, Pupun Saepul, et al.
Publicado: (2021)

Effect of D614G Spike Variant on Immunoglobulin G, M, or A Spike Seroassay Performance
por: Klumpp-Thomas, Carleen, et al.
Publicado: (2020)

Non-cancer-related pathogenic germline variants and expression consequences in ten-thousand cancer genomes
por: Wang, Zishan, et al.
Publicado: (2021)

High-throughput screening of spike variants uncovers the key residues that alter the affinity and antigenicity of SARS-CoV-2
por: Luo, Yufeng, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ncapmo5sti487nmg5s1ekft0k1