Cargando…
The Impact of Esophageal Oncological Surgery on Perioperative Immune Function; Implications for Adjuvant Immune Checkpoint Inhibition
BACKGROUND: Immune checkpoint inhibitors (ICIs) are being investigated for their role as an adjunct in the multimodal treatment of esophageal adenocarcinoma (EAC). The most effective time to incorporate ICIs remains unknown. Our study profiles systemic anti-tumor immunity perioperatively to help inf...
Autores principales: | Donlon, Noel E., Davern, Maria, Sheppard, Andrew D., O’Connell, Fiona, Dunne, Margaret R., Hayes, Conall, Mylod, Eimear, Ramjit, Sinead, Temperley, Hugo, Mac Lean, Michael, Cotter, Gillian, Bhardwaj, Anshul, Butler, Christine, Conroy, Melissa J., O’Sullivan, Jacintha, Ravi, Narayanasamy, Donohoe, Claire L., Reynolds, John V., Lysaght, Joanne |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829578/ https://www.ncbi.nlm.nih.gov/pubmed/35154142 http://dx.doi.org/10.3389/fimmu.2022.823225 |
Ejemplares similares
-
Impact of radiotherapy on the immune landscape in oesophageal adenocarcinoma
por: Donlon, Noel E, et al.
Publicado: (2022) -
Cooperation between chemotherapy and immune checkpoint blockade to enhance anti-tumour T cell immunity in oesophageal adenocarcinoma
por: Davern, Maria, et al.
Publicado: (2022) -
Nutrient deprivation and hypoxia alter T cell immune checkpoint expression: potential impact for immunotherapy
por: Davern, Maria, et al.
Publicado: (2022) -
Acidosis significantly alters immune checkpoint expression profiles of T cells from oesophageal adenocarcinoma patients
por: Davern, Maria, et al.
Publicado: (2022) -
The Prognostic Value of the Lymph Node in Oesophageal Adenocarcinoma; Incorporating Clinicopathological and Immunological Profiling
por: Donlon, Noel E., et al.
Publicado: (2021)