T cell immune awakening in response to immunotherapy is age-dependent

BACKGROUND: Precision immuno-oncology approaches are needed to improve cancer care. We recently demonstrated that in patients with metastatic melanoma, an increase of clonality or diversity of the T cell receptor (TCR) repertoire of peripheral T cells following one cycle of immunotherapy is coincide...

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Detalles Bibliográficos
Autores principales: Salih, Zena, Banyard, Antonia, Tweedy, Joshua, Galvani, Elena, Middlehurst, Philippa, Mills, Sarah, Weightman, John, Gupta, Avinash, Lorigan, Paul C., Zhou, Cong, Dhomen, Nathalie, Valpione, Sara, Marais, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829752/
https://www.ncbi.nlm.nih.gov/pubmed/34952479
http://dx.doi.org/10.1016/j.ejca.2021.11.015

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