Flow cytometric analysis of CD4+ T cell reactivation following anti-PD1 immunotherapy in a transgenic mouse model

This protocol uses the Tg4 Nr4a3-Tocky mouse model to recalibrate T cell activation thresholds and reveals the role that immune checkpoints play in controlling T cell activation. The example approach here uses flow cytometry to characterize quantitative and qualitative changes in splenic CD4(+) T ce...

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Detalles Bibliográficos
Autores principales: Sheriff, Lozan, Bending, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829797/
https://www.ncbi.nlm.nih.gov/pubmed/35169717
http://dx.doi.org/10.1016/j.xpro.2022.101161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829797/
https://www.ncbi.nlm.nih.gov/pubmed/35169717
http://dx.doi.org/10.1016/j.xpro.2022.101161

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