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Highly Stable Polymer Coating on Silver Nanoparticles for Efficient Plasmonic Enhancement of Fluorescence
[Image: see text] Surface coating of plasmonic nanoparticles is of huge importance to suppress fluorescence quenching in plasmon-enhanced fluorescence sensing. Herein, a one-pot method for synthesizing polymer-coated silver nanoparticles was developed using a functional polymer conjugated with disul...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829869/ https://www.ncbi.nlm.nih.gov/pubmed/35155921 http://dx.doi.org/10.1021/acsomega.1c06010 |
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author | Kato, Ryo Uesugi, Mitsuhiro Komatsu, Yoshie Okamoto, Fusatoshi Tanaka, Takuo Kitawaki, Fumihisa Yano, Taka-aki |
author_facet | Kato, Ryo Uesugi, Mitsuhiro Komatsu, Yoshie Okamoto, Fusatoshi Tanaka, Takuo Kitawaki, Fumihisa Yano, Taka-aki |
author_sort | Kato, Ryo |
collection | PubMed |
description | [Image: see text] Surface coating of plasmonic nanoparticles is of huge importance to suppress fluorescence quenching in plasmon-enhanced fluorescence sensing. Herein, a one-pot method for synthesizing polymer-coated silver nanoparticles was developed using a functional polymer conjugated with disulfide-containing anchoring groups. The disulfides played a crucial role in covalently bonding polymers to the surface of the silver nanoparticles. The covalent bond enabled the polymer layer to form a long-term stable coating on the silver nanoparticles. The polymer layer coated was adequately thin to efficiently achieve plasmonic enhancement of fluorescence and also thick enough to effectively suppress quenching of fluorescence, achieving a huge net enhancement of fluorescence. The polymer-coated plasmonic nanoparticles are a promising platform for demonstrating highly sensitive biosensing for medical diagnostics. |
format | Online Article Text |
id | pubmed-8829869 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | American Chemical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-88298692022-02-11 Highly Stable Polymer Coating on Silver Nanoparticles for Efficient Plasmonic Enhancement of Fluorescence Kato, Ryo Uesugi, Mitsuhiro Komatsu, Yoshie Okamoto, Fusatoshi Tanaka, Takuo Kitawaki, Fumihisa Yano, Taka-aki ACS Omega [Image: see text] Surface coating of plasmonic nanoparticles is of huge importance to suppress fluorescence quenching in plasmon-enhanced fluorescence sensing. Herein, a one-pot method for synthesizing polymer-coated silver nanoparticles was developed using a functional polymer conjugated with disulfide-containing anchoring groups. The disulfides played a crucial role in covalently bonding polymers to the surface of the silver nanoparticles. The covalent bond enabled the polymer layer to form a long-term stable coating on the silver nanoparticles. The polymer layer coated was adequately thin to efficiently achieve plasmonic enhancement of fluorescence and also thick enough to effectively suppress quenching of fluorescence, achieving a huge net enhancement of fluorescence. The polymer-coated plasmonic nanoparticles are a promising platform for demonstrating highly sensitive biosensing for medical diagnostics. American Chemical Society 2022-01-07 /pmc/articles/PMC8829869/ /pubmed/35155921 http://dx.doi.org/10.1021/acsomega.1c06010 Text en © 2022 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by-nc-nd/4.0/Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Kato, Ryo Uesugi, Mitsuhiro Komatsu, Yoshie Okamoto, Fusatoshi Tanaka, Takuo Kitawaki, Fumihisa Yano, Taka-aki Highly Stable Polymer Coating on Silver Nanoparticles for Efficient Plasmonic Enhancement of Fluorescence |
title | Highly Stable Polymer Coating on Silver Nanoparticles
for Efficient Plasmonic Enhancement of Fluorescence |
title_full | Highly Stable Polymer Coating on Silver Nanoparticles
for Efficient Plasmonic Enhancement of Fluorescence |
title_fullStr | Highly Stable Polymer Coating on Silver Nanoparticles
for Efficient Plasmonic Enhancement of Fluorescence |
title_full_unstemmed | Highly Stable Polymer Coating on Silver Nanoparticles
for Efficient Plasmonic Enhancement of Fluorescence |
title_short | Highly Stable Polymer Coating on Silver Nanoparticles
for Efficient Plasmonic Enhancement of Fluorescence |
title_sort | highly stable polymer coating on silver nanoparticles
for efficient plasmonic enhancement of fluorescence |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829869/ https://www.ncbi.nlm.nih.gov/pubmed/35155921 http://dx.doi.org/10.1021/acsomega.1c06010 |
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