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Identification and Optimization of a Novel HIV-1 Integrase Inhibitor

[Image: see text] Human immunodeficiency virus-1 (HIV-1) is the causative agent of acquired immunodeficiency syndrome (AIDS). HIV-1, like all retroviruses, stably integrates its vDNA copy into host chromatin, a process allowing for permanent infection. This essential step for HIV-1 replication is ca...

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Detalles Bibliográficos
Autores principales: Adu-Ampratwum, Daniel, Pan, Yuhan, Koneru, Pratibha C., Antwi, Janet, Hoyte, Ashley C., Kessl, Jacques, Griffin, Patrick R., Kvaratskhelia, Mamuka, Fuchs, James R., Larue, Ross C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829933/
https://www.ncbi.nlm.nih.gov/pubmed/35155940
http://dx.doi.org/10.1021/acsomega.1c06378