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Single-cell transcriptome analysis revealed a suppressive tumor immune microenvironment in EGFR mutant lung adenocarcinoma

BACKGROUNDS: Immunotherapy is less effective in patients with epidermal growth factor receptor (EGFR) mutant non-small-cell lung cancer (NSCLC). Lower programmed cell death-ligand 1 (PD-L1) expression and tumor mutation burden (TMB) are reported to be the underlying mechanism. Being another importan...

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Detalles Bibliográficos
Autores principales:	Yang, Lei, He, Yun-Ting, Dong, Song, Wei, Xue-Wu, Chen, Zhi-Hong, Zhang, Bo, Chen, Wei-Dong, Yang, Xiao-Rong, Wang, Fen, Shang, Xue-Meng, Zhong, Wen-Zhao, Wu, Yi-Long, Zhou, Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Immunotherapy Biomarkers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830346/ https://www.ncbi.nlm.nih.gov/pubmed/35140113 http://dx.doi.org/10.1136/jitc-2021-003534

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