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Hypertrophic Cardiomyopathy and Atrial Fibrillation: A Review
Hypertrophic cardiomyopathy (HCM) is an inherited cardiological condition that exhibits various clinical symptoms. The leading cause of atrial fibrillation (AF) in patients with HCM is advanced diastolic dysfunction and left atrial dilatation and remodeling. In addition to the gradual symptomatic an...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830388/ https://www.ncbi.nlm.nih.gov/pubmed/35165560 http://dx.doi.org/10.7759/cureus.21101 |
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author | Palyam, Vishnu Azam, Ahmad T Odeyinka, Oladipo Alhashimi, Rasha Thoota, Sankeerth Ashok, Tejaswini Sange, Ibrahim |
author_facet | Palyam, Vishnu Azam, Ahmad T Odeyinka, Oladipo Alhashimi, Rasha Thoota, Sankeerth Ashok, Tejaswini Sange, Ibrahim |
author_sort | Palyam, Vishnu |
collection | PubMed |
description | Hypertrophic cardiomyopathy (HCM) is an inherited cardiological condition that exhibits various clinical symptoms. The leading cause of atrial fibrillation (AF) in patients with HCM is advanced diastolic dysfunction and left atrial dilatation and remodeling. In addition to the gradual symptomatic and functional decline caused by AF, there is an increased risk of thromboembolic disease and mortality, especially if there is a rapid ventricular rate or obstruction of the left ventricular outflow tract. The mainstay of management of AF in HCM is a combination of non-pharmacological lifestyle and risk factor modification, long-term anticoagulation, and rhythm control with anti-arrhythmic medications, septal ablation, and radiofrequency catheter ablation. This article has examined the development of AF in HCM, its clinical symptomatology, and its impact, highlighting its management and the mortality associated with AF in HCM. |
format | Online Article Text |
id | pubmed-8830388 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-88303882022-02-13 Hypertrophic Cardiomyopathy and Atrial Fibrillation: A Review Palyam, Vishnu Azam, Ahmad T Odeyinka, Oladipo Alhashimi, Rasha Thoota, Sankeerth Ashok, Tejaswini Sange, Ibrahim Cureus Cardiology Hypertrophic cardiomyopathy (HCM) is an inherited cardiological condition that exhibits various clinical symptoms. The leading cause of atrial fibrillation (AF) in patients with HCM is advanced diastolic dysfunction and left atrial dilatation and remodeling. In addition to the gradual symptomatic and functional decline caused by AF, there is an increased risk of thromboembolic disease and mortality, especially if there is a rapid ventricular rate or obstruction of the left ventricular outflow tract. The mainstay of management of AF in HCM is a combination of non-pharmacological lifestyle and risk factor modification, long-term anticoagulation, and rhythm control with anti-arrhythmic medications, septal ablation, and radiofrequency catheter ablation. This article has examined the development of AF in HCM, its clinical symptomatology, and its impact, highlighting its management and the mortality associated with AF in HCM. Cureus 2022-01-11 /pmc/articles/PMC8830388/ /pubmed/35165560 http://dx.doi.org/10.7759/cureus.21101 Text en Copyright © 2022, Palyam et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Cardiology Palyam, Vishnu Azam, Ahmad T Odeyinka, Oladipo Alhashimi, Rasha Thoota, Sankeerth Ashok, Tejaswini Sange, Ibrahim Hypertrophic Cardiomyopathy and Atrial Fibrillation: A Review |
title | Hypertrophic Cardiomyopathy and Atrial Fibrillation: A Review |
title_full | Hypertrophic Cardiomyopathy and Atrial Fibrillation: A Review |
title_fullStr | Hypertrophic Cardiomyopathy and Atrial Fibrillation: A Review |
title_full_unstemmed | Hypertrophic Cardiomyopathy and Atrial Fibrillation: A Review |
title_short | Hypertrophic Cardiomyopathy and Atrial Fibrillation: A Review |
title_sort | hypertrophic cardiomyopathy and atrial fibrillation: a review |
topic | Cardiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830388/ https://www.ncbi.nlm.nih.gov/pubmed/35165560 http://dx.doi.org/10.7759/cureus.21101 |
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