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Interaction of TLK1 and AKTIP as a Potential Regulator of AKT Activation in Castration-Resistant Prostate Cancer Progression

Prostate cancer (PCa) progression is characterized by the emergence of resistance to androgen deprivation therapy (ADT). AKT/PKB has been directly implicated in PCa progression, often due to the loss of PTEN and activation of PI3K>PDK1>AKT signaling. However, the regulatory network of AKT rema...

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Detalles Bibliográficos
Autores principales:	Khalil, Md Imtiaz, Madere, Christopher, Ghosh, Ishita, Adam, Rosalyn M., De Benedetti, Arrigo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830441/ https://www.ncbi.nlm.nih.gov/pubmed/35366279 http://dx.doi.org/10.3390/pathophysiology28030023

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