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Amyloid Beta Peptides and Th1 Cytokines Modulate Human Brain Vascular Smooth Muscle Tonic Contractile Capacity In Vitro: Relevance to Alzheimer’s Disease?

Alzheimer’s Disease (AD) is a neurodegenerative condition characterized both by the presence of tau protein neurofibrillary tangles and amyloid beta (Aβ) containing extracellular “plaques”. The cleavage of amyloid precursor protein (APP) yields several Aβ peptides. Although Aβ toxicity to neurons ha...

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Detalles Bibliográficos
Autores principales: Yun, J. Winny, Washington, Caretia, McCormick, Joi, Stevenson, Emily, Alexander, J. Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830442/
https://www.ncbi.nlm.nih.gov/pubmed/35366270
http://dx.doi.org/10.3390/pathophysiology28010006