Cargando…

Pathophysiology of Lung Disease and Wound Repair in Cystic Fibrosis

Cystic fibrosis (CF) is an autosomal recessive, life-threatening condition affecting many organs and tissues, the lung disease being the chief cause of morbidity and mortality. Mutations affecting the CF Transmembrane Conductance Regulator (CFTR) gene determine the expression of a dysfunctional prot...

Descripción completa

Detalles Bibliográficos
Autores principales:	Conese, Massimo, Di Gioia, Sante
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830450/ https://www.ncbi.nlm.nih.gov/pubmed/35366275 http://dx.doi.org/10.3390/pathophysiology28010011

Ejemplares similares

Extracellular Vesicles’ Role in the Pathophysiology and as Biomarkers in Cystic Fibrosis and COPD
por: Di Gioia, Sante, et al.
Publicado: (2022)

Lung Inflammatory Genes in Cystic Fibrosis and Their Relevance to Cystic Fibrosis Transmembrane Conductance Regulator Modulator Therapies
por: Carbone, Annalucia, et al.
Publicado: (2023)

Human Cellular Models for the Investigation of Lung Inflammation and Mucus Production in Cystic Fibrosis
por: Castellani, Stefano, et al.
Publicado: (2018)

Human Amniotic Mesenchymal Stem Cells and Fibroblasts Accelerate Wound Repair of Cystic Fibrosis Epithelium
por: Beccia, Elisa, et al.
Publicado: (2022)

Elexacaftor/Tezacaftor/Ivacaftor Accelerates Wound Repair in Cystic Fibrosis Airway Epithelium
por: Laselva, Onofrio, et al.
Publicado: (2022)

Polyethylenimine-mediated gene delivery to the lung and therapeutic applications
por: Di Gioia, Sante, et al.
Publicado: (2009)

Anti-Inflammatory and Anti-Oxidant Effect of Dimethyl Fumarate in Cystic Fibrosis Bronchial Epithelial Cells
por: Laselva, Onofrio, et al.
Publicado: (2021)

Insulin-Like Growth Factor Binding Protein (IGFBP-6) as a Novel Regulator of Inflammatory Response in Cystic Fibrosis Airway Cells
por: Laselva, Onofrio, et al.
Publicado: (2022)

Isolation and characterization of microparticles in sputum from cystic fibrosis patients
por: Porro, Chiara, et al.
Publicado: (2010)

Lentiviral Vectors and Cystic Fibrosis Gene Therapy
por: Castellani, Stefano, et al.
Publicado: (2010)

Molecular links between endocrine, nervous and immune system during chronic stress
por: Zefferino, Roberto, et al.
Publicado: (2020)

Biological properties and therapeutic effects of plant-derived nanovesicles
por: Di Gioia, Sante, et al.
Publicado: (2020)

How Cells Communicate with Each Other in the Tumor Microenvironment: Suggestions to Design Novel Therapeutic Strategies in Cancer Disease
por: Zefferino, Roberto, et al.
Publicado: (2021)

Correction of defective CFTR/ENaC function and tightness of cystic fibrosis airway epithelium by amniotic mesenchymal stromal (stem) cells
por: Carbone, Annalucia, et al.
Publicado: (2014)

Hematopoietic and Mesenchymal Stem Cells for the Treatment of Chronic Respiratory Diseases: Role of Plasticity and Heterogeneity
por: Conese, Massimo, et al.
Publicado: (2014)

Not All Is CFTR – Neutrophils and Cholesterol in Cystic Fibrosis
por: Castellani, Stefano, et al.
Publicado: (2017)

Gap Junction Intercellular Communication in the Carcinogenesis Hallmarks: Is This a Phenomenon or Epiphenomenon?
por: Zefferino, Roberto, et al.
Publicado: (2019)

Amniotic Mesenchymal Stem Cells: A New Source for Hepatocyte-Like Cells and Induction of CFTR Expression by Coculture with Cystic Fibrosis Airway Epithelial Cells
por: Paracchini, Valentina, et al.
Publicado: (2012)

G-CSF and GM-CSF Modify Neutrophil Functions at Concentrations found in Cystic Fibrosis
por: Castellani, Stefano, et al.
Publicado: (2019)

Gap Junctions Are Involved in the Rescue of CFTR-Dependent Chloride Efflux by Amniotic Mesenchymal Stem Cells in Coculture with Cystic Fibrosis CFBE41o- Cells
por: Carbone, Annalucia, et al.
Publicado: (2018)

Magnetofection Enhances Lentiviral-Mediated Transduction of Airway Epithelial Cells through Extracellular and Cellular Barriers
por: Castellani, Stefano, et al.
Publicado: (2016)

Evaluation of Genome-Wide Expression Profiles of Blood and Sputum Neutrophils in Cystic Fibrosis Patients Before and After Antibiotic Therapy
por: Conese, Massimo, et al.
Publicado: (2014)

Editorial: Mechanisms of Novel Drugs and Gene Modifiers in the Treatment of Cystic Fibrosis
por: Veit, Guido, et al.
Publicado: (2022)

Impact of Lentiviral Vector-Mediated Transduction on the Tightness of a Polarized Model of Airway Epithelium and Effect of Cationic Polymer Polyethylenimine
por: Castellani, Stefano, et al.
Publicado: (2010)

Epithelial mesenchymal transition (EMT): a universal process in lung diseases with implications for cystic fibrosis pathophysiology
por: Rout-Pitt, Nathan, et al.
Publicado: (2018)

The Role of Adipose-Derived Stem Cells, Dermal Regenerative Templates, and Platelet-Rich Plasma in Tissue Engineering-Based Treatments of Chronic Skin Wounds
por: Conese, Massimo, et al.
Publicado: (2020)

Blood Clotting Dissolution in the Presence of a Magnetic Field and Preliminary Study with MG63 Osteoblast-like Cells—Further Developments for Guided Bone Regeneration?
por: Di Gioia, Sante, et al.
Publicado: (2023)

Cystic Fibrosis–Related Diabetes: Pathophysiology and Therapeutic Challenges
por: Kelsey, Ryan, et al.
Publicado: (2019)

Assessment of Stress Salivary Markers, Perceived Stress, and Shift Work in a Cohort of Fishermen: A Preliminary Work
por: Zefferino, Roberto, et al.
Publicado: (2022)

Animal Models in the Pathophysiology of Cystic Fibrosis
por: Semaniakou, Anna, et al.
Publicado: (2019)

Sex disparities in cystic fibrosis: review on the effect of female sex hormones on lung pathophysiology and outcomes
por: Lam, Grace Y., et al.
Publicado: (2021)

COVID-19: Pathophysiology and implications for cystic fibrosis, diabetes and cystic fibrosis-related diabetes
por: Mason, Kelly, et al.
Publicado: (2021)

The Oncogenic Theory of Preeclampsia: Is Amniotic Mesenchymal Stem Cells-Derived PLAC1 Involved?
por: Conese, Massimo, et al.
Publicado: (2023)

The diversity of myeloid immune cells shaping wound repair and fibrosis in the lung
por: Florez‐Sampedro, Laura, et al.
Publicado: (2018)

Pathophysiology of Cystic Fibrosis Liver Disease: A Channelopathy Leading to Alterations in Innate Immunity and in Microbiota
por: Fiorotto, Romina, et al.
Publicado: (2019)

Lung Microbiome in Cystic Fibrosis
por: Scialo, Filippo, et al.
Publicado: (2021)

Cystic fibrosis-related diabetes and lung disease: an update
por: Prentice, Bernadette J., et al.
Publicado: (2021)

Insulin-Like Growth Factor Binding Protein 6 Is Secreted in Extracellular Vesicles upon Hyperthermia and Oxidative Stress in Dendritic Cells But Not in Monocytes
por: Conese, Massimo, et al.
Publicado: (2020)

Downregulation of exosomal let-7d and miR-16 in idiopathic pulmonary fibrosis
por: Lacedonia, Donato, et al.
Publicado: (2021)

Biomarkers in Cystic Fibrosis Lung Disease – A Review
por: Ciuca, Ioana Mihaiela, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_3314eleb0e7vpkh34ke35ls9c1